4-Bromomethyl-2-chloro-1-methoxybenzene

Base Information

• Chemical Name: 4-Bromomethyl-2-chloro-1-methoxybenzene
• CAS No.: 320407-92-9
• Molecular Formula: C8H8BrClO
• Molecular Weight: 235.508
• Hs Code.: 2909309090
• European Community (EC) Number: 801-104-6
• DSSTox Substance ID: DTXSID70466932
• Wikidata: Q82293605
• Mol file: 320407-92-9.mol

Synonyms:320407-92-9;4-Bromomethyl-2-chloro-1-methoxybenzene;4-(bromomethyl)-2-chloro-1-methoxybenzene;3-CHLORO-4-METHOXYBENZYL BROMIDE;Benzene, 4-(bromomethyl)-2-chloro-1-methoxy-;MFCD06858766;SCHEMBL365268;3-chloro-4-methoxybenzylbromide;4-(Bromomethyl)-2-chloroanisole;DTXSID70466932;BDYJMOYDXJQHFS-UHFFFAOYSA-N;3-chloro-4-methoxy-benzyl bromide;CL8903;AKOS010948712;CS-W005817;GS-3827;SY110867;EN300-119082;A875729

Chemical Property of 4-Bromomethyl-2-chloro-1-methoxybenzene

Chemical Property:

• Vapor Pressure: 0.01mmHg at 25°C
• Boiling Point: 272.95oC at 760 mmHg
• Flash Point: 118.876oC
• PSA: 9.23000
• Density: 1.521g/cm3
• LogP: 3.24350
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 233.94471
• Heavy Atom Count: 11
• Complexity: 121

Purity/Quality:

97% ^*data from raw suppliers

4-Bromomethyl-2-chloro-1-methoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)CBr)Cl

Technology Process of 4-Bromomethyl-2-chloro-1-methoxybenzene

There total 6 articles about 4-Bromomethyl-2-chloro-1-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

→ 4-(bromomethyl)-2-chloro-1-methoxybenzene (320407-92-9)

Guidance literature:

Reference yield: 82.0%

2-chloro-1-methoxy-4-methylbenzene (22002-44-4) → 4-(bromomethyl)-2-chloro-1-methoxybenzene (320407-92-9)

Guidance literature:

With azobisisobutyronitrile; In N-Bromosuccinimide; water;

Reference yield:

3-chloro-4-methoxybenzyl alcohol (14503-45-8) → 4-(bromomethyl)-2-chloro-1-methoxybenzene (320407-92-9)

Guidance literature:

With hydrogen bromide;

DOI:10.1039/jr9380001780

upstream raw materials:

3-chloro-4-methoxybenzyl alcohol

4-methoxyphenethyl bromide

C₈H₈ClO⁽¹⁺⁾

p-(methylthio)phenethyl bromide

Downstream raw materials:

3-chloro-4-methoxy-benzenemethanethiol

2-(3-chloro-4-methoxyphenyl)acetonitrile

C₁₅H₁₂ClFN₂O

tert-butyl 3-chloro-N-(diphenylmethylene)-O-methyl-D-tyrosinate