N-[2-(Diphenylphosphino)benzylidene]cyclohexylamine

Base Information

• Chemical Name: N-[2-(Diphenylphosphino)benzylidene]cyclohexylamine
• CAS No.: 321155-13-9
• Molecular Formula: C25H26NP
• Molecular Weight: 371.462
• Hs Code.: 2931900090
• European Community (EC) Number: 805-564-9
• Nikkaji Number: J1.470.596A
• Mol file: 321155-13-9.mol

Synonyms:321155-13-9;N-[2-(Diphenylphosphino)benzylidene]cyclohexylamine;N-cyclohexyl-1-(2-diphenylphosphanylphenyl)methanimine;(NE)-N-{[2-(Diphenylphosphanyl)phenyl]-methylidene}cyclohexanamine;(E)-N-Cyclohexyl-1-(2-(diphenylphosphaneyl)phenyl)methanimine;(1E)-N-cyclohexyl-1-[2-(diphenylphosphanyl)phenyl]methanimine;1312236-53-5;SCHEMBL2002755;SCHEMBL16772933;MFCD16251547;AKOS025295142;AS-2000;N-[2-(Diphenylphosphino)benzylidene]cyclohexylamine, 97%;(Ne)-n-([2-(diphenylphosphanyl)phenyl]methylidene)cyclohexanamine

Chemical Property of N-[2-(Diphenylphosphino)benzylidene]cyclohexylamine

Chemical Property:

• Melting Point: 116-120°C
• PSA: 25.95000
• LogP: 5.19640
• XLogP3: 6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 371.180286831
• Heavy Atom Count: 27
• Complexity: 425

Purity/Quality:

99% ^*data from raw suppliers

N-[2-(Diphenylphosphino)benzylidene]cyclohexylamine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCC(CC1)N=CC2=CC=CC=C2P(C3=CC=CC=C3)C4=CC=CC=C4
• Uses: Catalyst for:Cross-coupling reactionsStannylative cycloaddition of conjugated enynesStereo- and regioselective alkynylstannylation of alkynes

Technology Process of N-[2-(Diphenylphosphino)benzylidene]cyclohexylamine

There total 1 articles about N-[2-(Diphenylphosphino)benzylidene]cyclohexylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(2-formylphenyl)(diphenyl)phosphine (50777-76-9) + cyclohexylamine (108-91-8,157973-60-9) → N-cyclohexyl-1-[2-(diphenylphosphanyl)phenyl]methanimine (321155-13-9)

Guidance literature:

In dichloromethane; at 20 ℃; for 12h;

DOI:10.1039/c1gc15979h

Reference yield: 99.0%

bis(1,5-cyclooctadiene)nickel (0) (1295-35-8) + N-cyclohexyl-1-[2-(diphenylphosphanyl)phenyl]methanimine (321155-13-9) + ethyl 2-benzylidene acetoacetate (620-80-4) → ((C6H5)2PC6H4CHNC6H11)Ni(CH3CH2OC(O)C(C(O)CH3)CC6H5) (1312236-54-6)

Guidance literature:

In toluene; 25 °C;

DOI:10.1039/c1cc10890e

Reference yield: 99.0%

bis(1,5-cyclooctadiene)nickel (0) (1295-35-8) + N-cyclohexyl-1-[2-(diphenylphosphanyl)phenyl]methanimine (321155-13-9) + ethyl 2-benzylidene acetoacetate (620-80-4) → (C6H5)2PC6H4CHNC6H11NiOCCH3C(COOC2H5)CHC6H5 (1312236-54-6)

Guidance literature:

In toluene; stoich., ligands reacted with Ni(COD02 in toluene at room temp. for 15 min;

DOI:10.1246/cl.2011.808

upstream raw materials:

(2-formylphenyl)(diphenyl)phosphine

cyclohexylamine

Downstream raw materials:

[(E)-2-(diphenylphosphanyl)-N-cyclohexylbenzimino-C,P]tris(trimethylphosphane)cobalt(I)

[Pd[3,4-(MeO)2C₆H₂C(H)=N(Cy)-C₆,N)(Ph₂PC₆H₄C(H)=NC₆H₁₁-P,N)][ClO₄]

((C₆H₅)2PC₆H₄CHNC₆H₁₁)Ni(CH₃CH₂OC(O)C(C(O)CH₃)CC₆H₅)

(C₆H₅)2PC₆H₄CHNC₆H₁₁NiOCCH₃C(COOC₂H₅)CHC₆H₅

Refernces