Ethyl 2-(phenylmethyl)benzeneacetate

Base Information

• Chemical Name: Ethyl 2-(phenylmethyl)benzeneacetate
• CAS No.: 108976-72-3
• Molecular Formula: C₁₇H₁₈O₂
• Molecular Weight: 254.329
• DSSTox Substance ID: DTXSID001289655
• Mol file: 108976-72-3.mol

Synonyms:Ethyl 2-(phenylmethyl)benzeneacetate;DTXSID001289655;108976-72-3

Chemical Property of Ethyl 2-(phenylmethyl)benzeneacetate

Chemical Property:

• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 254.130679813
• Heavy Atom Count: 19
• Complexity: 268

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)CC1=CC=CC=C1CC2=CC=CC=C2

Technology Process of Ethyl 2-(phenylmethyl)benzeneacetate

There total 4 articles about Ethyl 2-(phenylmethyl)benzeneacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + 2-(2-benzylphenyl)acetic acid (36374-49-9) → ethyl o-benzylphenylacetate (108976-72-3)

Guidance literature:

Acidic conditions;

Reference yield:

ethyl 2,4-diphenyl-3-oxobutanoate (2901-29-3) → ethyl 2,3-diphenylpropionate (5415-85-0) + diethyl meso-α,α'-diphenylsuccinate (3059-23-2) + ethyl o-benzylphenylacetate (108976-72-3) + 1,1'-(1,2-ethanediyl)bisbenzene (103-29-7) + ethyl o-(α-ethoxycarbonylbenzyl)phenylacetate (81711-08-2)

Guidance literature:

In benzene; for 1h; Irradiation; photochemical reaction, other solvent, also under oxygen;

DOI:10.1246/bcsj.55.877

Reference yield:

→ ethyl o-benzylphenylacetate (108976-72-3)

Guidance literature:

2-Benzyl-ω-diazo-acetophenon, A., Ag2O, 50-60grad;

upstream raw materials:

ethyl 2,4-diphenyl-3-oxobutanoate

ethanol

2-(2-benzylphenyl)acetic acid

ethyl 2-(2-methylphenyl)acetate

Downstream raw materials:

5[2'-(benzyl)phenyl]propionic acid

2-(2'-benzyl)phenylethyl alcohol