5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one

Base Information

Chemical Name:5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one
CAS No.:32278-40-3
Molecular Formula:C₁₂H₈N₂OS
Molecular Weight:228.274
Hs Code.:
European Community (EC) Number:662-874-5
Mol file:32278-40-3.mol

Synonyms:32278-40-3;5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one;AKOS024328265;5-PHENYL-7H-(1,3)THIAZOLO(3,2-A)PYRIMIDIN-7-ONE

Suppliers and Price of 5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:228.03573406
Heavy Atom Count:16
Complexity:405

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)N=C3N2C=CS3

Technology Process of 5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one

There total 2 articles about 5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96-50-4
2-thiazolylamine

: 2216-94-6
phenylpropynoic acid ethyl ester

: 32278-40-3
5-phenyl-thiazolo[3,2-a]pyrimidin-7-one

Guidance literature:: With tetramethyl ammoniumhydroxide; In ethanol;
DOI:10.1039/j39710002094

Reference yield:

: 7299-58-3
phenylpropiolyl chloride

: 32278-40-3
5-phenyl-thiazolo[3,2-a]pyrimidin-7-one

Guidance literature:: Multi-step reaction with 2 steps

1: CHCl₃

2: H₂SO₄ / 5 h / 55 °C

With sulfuric acid; In chloroform;
DOI:10.1248/cpb.20.1716