CARBAMIC ACID, [4-(BROMOMETHYL)-2-FLUOROPHENYL]-, 1,1-DIMETHYLETHYL ESTER

Base Information

Chemical Name:CARBAMIC ACID, [4-(BROMOMETHYL)-2-FLUOROPHENYL]-, 1,1-DIMETHYLETHYL ESTER
CAS No.:323578-36-5
Molecular Formula:C12H15BrFNO2
Molecular Weight:304.159
Hs Code.:2916399090
Mol file:323578-36-5.mol

Synonyms:

Suppliers and Price of CARBAMIC ACID, [4-(BROMOMETHYL)-2-FLUOROPHENYL]-, 1,1-DIMETHYLETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Amino-3-fluorobenzyl bromide, N-Boc protected
1 g
$ 544.00

SynQuest Laboratories
4-Amino-3-fluorobenzyl bromide, N-Boc protected
250 mg
$ 256.00

SynQuest Laboratories
4-Amino-3-fluorobenzyl bromide, N-Boc protected
5 g
$ 1568.00

Labseeker
Carbamicacid,[4-(bromomethyl)-2-fluorophenyl]-,1,1-dimethylethylester(9Cl) 95
10g
$ 2475.00

Apolloscientific
4-Amino-3-fluorobenzylbromide,N-BOCprotected
5g
$ 1421.00

Apolloscientific
4-Amino-3-fluorobenzylbromide,N-BOCprotected
250mg
$ 183.00

Total 3 raw suppliers

Chemical Property of CARBAMIC ACID, [4-(BROMOMETHYL)-2-FLUOROPHENYL]-, 1,1-DIMETHYLETHYL ESTER

Chemical Property:

Boiling Point:299.4±35.0 °C(Predicted)
PKA:12.41±0.70(Predicted)
PSA：38.33000
Density:1.433±0.06 g/cm3(Predicted)
LogP:4.14060

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-3-fluorobenzyl bromide, N-Boc protected ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of CARBAMIC ACID, [4-(BROMOMETHYL)-2-FLUOROPHENYL]-, 1,1-DIMETHYLETHYL ESTER

There total 3 articles about CARBAMIC ACID, [4-(BROMOMETHYL)-2-FLUOROPHENYL]-, 1,1-DIMETHYLETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 323578-35-4
tert-butyl 2-fluoro-4-methylphenylcarbamate

: 323578-36-5
tert-butyl (4-(bromomethyl)-2-fluorophenyl)carbamate

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; at 85 ℃; for 4h;
DOI:10.1021/jm0003135

Reference yield:

: 446-34-4
2-fluoro-4-methyl-1-nitrobenzene

: 323578-36-5
tert-butyl (4-(bromomethyl)-2-fluorophenyl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / 10percent Pd/C / ethanol / 3 h / 760.05 Torr

2: dioxane / 48 h / 100 °C

3: N-bromosuccinimide; benzoyl peroxide / CCl₄ / 4 h / 85 °C

With N-Bromosuccinimide; hydrogen; dibenzoyl peroxide; 10percent Pd/C; In 1,4-dioxane; tetrachloromethane; ethanol;
DOI:10.1021/jm0003135

Reference yield:

: 452-80-2
2-fluoro-4-methylaniline

: 323578-36-5
tert-butyl (4-(bromomethyl)-2-fluorophenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: dioxane / 48 h / 100 °C

2: N-bromosuccinimide; benzoyl peroxide / CCl₄ / 4 h / 85 °C

With N-Bromosuccinimide; dibenzoyl peroxide; In 1,4-dioxane; tetrachloromethane;
DOI:10.1021/jm0003135