4,4,5,5-Tetramethyl-2-(perfluorophenyl)-1,3,2-dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-Tetramethyl-2-(perfluorophenyl)-1,3,2-dioxaborolane
• CAS No.: 325142-81-2
• Molecular Formula: C12H12BF5O2
• Molecular Weight: 294.02500
• Hs Code.: 2934999090
• Mol file: 325142-81-2.mol

Synonyms:Perfluorophenylboronic acid,pinacol ester;4,4,5,5-tetramethyl-2-(2,3,4,5,6-pentafluorophenyl)-1,3,2-dioxaborolane;

Chemical Property of 4,4,5,5-Tetramethyl-2-(perfluorophenyl)-1,3,2-dioxaborolane

Chemical Property:

• Melting Point: 35-36℃
• Boiling Point: 66℃/0.4mm
• PSA: 18.46000
• Density: 1.28±0.1 g/cm3(Predicted)
• LogP: 2.68130
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4,4,5,5-Tetramethyl-2-(perfluorophenyl)-1,3,2-dioxaborolane 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4,5,5-Tetramethyl-2-(perfluorophenyl)-1,3,2-dioxaborolane

There total 13 articles about 4,4,5,5-Tetramethyl-2-(perfluorophenyl)-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Pentafluorobenzene (363-72-4) + bis(pinacol)diborane (73183-34-3) → 4,4,5,5-tetramethyl-2-(2,3,4,5,6-pentafluorophenyl)-1,3,2-dioxaborolane (325142-81-2)

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; 1-(4,4'-di-tert-butyl-[2,2'-bipyridin]-6-yl)-2-(dimethyl(phenyl)silyl)-2,3-dihydro-1H-benzo[d][1,3,2]diazaborole; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.3390/molecules24071434

Reference yield: 90.0%

pentafluorophenylborane + 2,3-dimethyl-2,3-butane diol (76-09-5) → 4,4,5,5-tetramethyl-2-(2,3,4,5,6-pentafluorophenyl)-1,3,2-dioxaborolane (325142-81-2)

Guidance literature:

In acetone; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol2022577

Reference yield: 82.0%

1-chloro-2,3,4,5,6-pentafluorobenzene (344-07-0) + bis(pinacol)diborane (73183-34-3) → 4,4,5,5-tetramethyl-2-(2,3,4,5,6-pentafluorophenyl)-1,3,2-dioxaborolane (325142-81-2)

Guidance literature:

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 105 ℃; for 18h; Sealed tube; Inert atmosphere;

DOI:10.1002/chem.202004648

upstream raw materials:

Pentafluorobenzene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

2,3-dimethyl-2,3-butane diol

pentafluorophenylboronic acid

Downstream raw materials:

2,3,4,5,6-pentafluoro-4'-methylbiphenyl

2,3,4,5,6-pentafluoro-3'-methylbiphenyl

2'-methyl-2,3,4,5,6-pentafluorobiphenyl

1-pentafluorophenyl-2-phenylacetylene