N-(2-Ethoxyethyl)benzylamine

Base Information

• Chemical Name: N-(2-Ethoxyethyl)benzylamine
• CAS No.: 67411-38-5
• Molecular Formula: C11H17NO
• Molecular Weight: 179.262
• European Community (EC) Number: 266-687-6
• DSSTox Substance ID: DTXSID30217765
• Nikkaji Number: J310.247E
• Wikidata: Q83094408
• Mol file: 67411-38-5.mol

Synonyms:N-(2-Ethoxyethyl)benzylamine;67411-38-5;N-benzyl-2-ethoxyethanamine;BENZYL(2-ETHOXYETHYL)AMINE;EINECS 266-687-6;SCHEMBL7574369;DTXSID30217765;N-(2-Ethoxyethyl)benzenemethanamine;AKOS004122825;EN300-162796;A1-05925

Chemical Property of N-(2-Ethoxyethyl)benzylamine

Chemical Property:

• Vapor Pressure: 0.0224mmHg at 25°C
• Boiling Point: 249.9°C at 760 mmHg
• Flash Point: 101.7°C
• PSA: 21.26000
• Density: 0.958g/cm³
• LogP: 2.20360
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 179.131014166
• Heavy Atom Count: 13
• Complexity: 111

Purity/Quality:

98%Min ^*data from raw suppliers

N-Benzyl-2-ethoxyethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOCCNCC1=CC=CC=C1

Technology Process of N-(2-Ethoxyethyl)benzylamine

There total 6 articles about N-(2-Ethoxyethyl)benzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-ethoxy-1-ethanamine (110-76-9) + benzaldehyde (100-52-7) → N-benzyl-2-ethoxyethanamine (67411-38-5)

Guidance literature:

With iron pentacarbonyl; potassium hydroxide; In ethanol; at 20 - 50 ℃; for 27h;

Reference yield: 36.0%

N-benzyl-N-(2-ethoxyethyl)ethanethioamide (1374247-13-8) + cyclohexylmagnesiumchloride (931-51-1) → N-benzyl-1-cyclohexyl-N-(2-ethoxyethyl)ethanamine (1374247-23-0) + N-benzyl-2-ethoxyethanamine (67411-38-5)

Guidance literature:

With titanium(IV) isopropylate; In tetrahydrofuran; at 0 - 20 ℃; for 1.16667h; Inert atmosphere;

DOI:10.1021/om500603v

Reference yield:

benzylidene-β-vinyloxyethylamine (67411-28-3) → N-benzyl-2-ethoxyethanamine (67411-38-5)

Guidance literature:

With hydrogen; nickel; In ethanol;

DOI:10.1007/BF00929034

upstream raw materials:

2-chloroethyl ethyl ether

benzylamine

2-ethoxyethyl p-toluenesulfonate

benzylidene-β-vinyloxyethylamine

Downstream raw materials:

dichloro-acetic acid-[(2-ethoxy-ethyl)-benzyl-amide]