Dithiophosphoric acid S,S'-bis-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O-(2-cyano-ethyl) ester

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Chemical Name:Dithiophosphoric acid S,S'-bis-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O-(2-cyano-ethyl) ester
CAS No.:141690-87-1
Molecular Formula:C₇₇H₆₈N₁₁O₁₀PS₂
Molecular Weight:1402.56
Hs Code.:

Dithiophosphoric acid S,S'-bis-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O-(2-cyano-ethyl) ester

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Chemical Property of Dithiophosphoric acid S,S'-bis-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O-(2-cyano-ethyl) ester

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Technology Process of Dithiophosphoric acid S,S'-bis-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O-(2-cyano-ethyl) ester

There total 1 articles about Dithiophosphoric acid S,S'-bis-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O-(2-cyano-ethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21090-30-2
3'-O-acetylthymidine

: 141690-83-7,141690-84-8
<2'-Deoxy-3'-thio-5'-O-(4-monomethoxytrityl)-6-N-benzoyladenosine>-3'-S-(2-cyanoethyl)-N,N-diisopropylphosphorothioamidite

: 141690-87-1
Dithiophosphoric acid S,S'-bis-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O-(2-cyano-ethyl) ester

: Diisopropyl-thiophosphoramidic acid S-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O-(2-cyano-ethyl) ester

: C₅₂H₅₁N₈O₁₂PS

Guidance literature:: With 2,6-dimethylpyridine; 5-(4-nitrophenyl)-1H-1,2,3,4-tetrazole; tetrabutylammonium periodite; Yield given. Multistep reaction. Yields of byproduct given; 1) MeCN, 15 min, 2) CH₂Cl₂, 7 min;
DOI:10.1016/S0040-4020(01)88532-X