Phosphorinane, 1-phenyl-

Base Information

• Chemical Name: Phosphorinane, 1-phenyl-
• CAS No.: 3302-83-8
• Molecular Formula: C11H15P
• Molecular Weight: 178.214
• Mol file: 3302-83-8.mol

Synonyms:

Chemical Property of Phosphorinane, 1-phenyl-

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphorinane, 1-phenyl-

There total 12 articles about Phosphorinane, 1-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

1-Phenylphosphinane 1-sulfide (4963-94-4) → 1-phenylphosphinane (3302-83-8)

Guidance literature:

With Raney-Ni; In ethanol; benzene; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1080/10426507.2016.1225052

Reference yield:

1,5-dibromo-pentane (111-24-0) + Dichlorophenylphosphine (644-97-3) → 1-phenylphosphinane (3302-83-8)

Guidance literature:

Multistep reaction; (i) Mg, THF, (ii) /BRN= 508189/;

DOI:10.1021/jo00933a017

Reference yield:

borane-THF (14044-65-6) + 1-phenylphosphorinane-1-oxide (4963-95-5) → 1-phenylphosphinane (3302-83-8) + 1-phenylphosphorinane-borane

Guidance literature:

With titanium(IV) isopropylate; In tetrahydrofuran; toluene; at 80 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.tet.2021.132057

upstream raw materials:

Dichlorophenylphosphine

pentamethylenebis(magnesium bromide)

P,P-dichlorophenylphosphine oxide

1,5-dibromo-pentane

Downstream raw materials:

trans-[RhCl(CO)(1-phenylphosphinane)2]

cis-[PtCl₂(1-phenylphosphinane)2]

(Z)-1,4-diphenyl-1-butene

(1E)-1,3-diphenylpropene

Refernces

• 1、 Priestley et al.. "-". . p. 618. Retrieved 1967.
• 2、 Sowa, Sylwia,Pietrusiewicz, K. Micha?. "Reduction of tertiary phosphine oxides to phosphine-boranes using Ti(Oi-Pr)4/BH3-THF". supporting information. . Retrieved 2021/03/17.
• 3、 Schirmer, Marie-Luis,Jopp, Stefan,Holz, Jens,Spannenberg, Anke,Werner, Thomas. "Organocatalyzed Reduction of Tertiary Phosphine Oxides". supporting information. p. 26 - 29. Retrieved 2016/01/25.