Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-2-methyl-, acetate

Base Information

• Chemical Name: Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-2-methyl-, acetate
• CAS No.: 19856-72-5
• Molecular Formula: C₁₇H₂₁NO₅
• Molecular Weight: 319.357
• Hs Code.: 2934999090
• Nikkaji Number: J41.787D
• Mol file: 19856-72-5.mol

Synonyms:BRN 4734757;19856-72-5;LG 50,177;Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-2-methyl-, acetate;[2-methoxy-4-[(E)-3-(2-methylmorpholin-4-yl)-3-oxoprop-1-enyl]phenyl] acetate;[2-methoxy-4-[(E)-3-(2-methylmorpholin-4-yl)-3-oxo-prop-1-enyl]phenyl] acetate;QQVYIGKECIIXSB-FNORWQNLSA-N;LG-50177;LS-93055;Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-2-methyl-, acetate (ester)

Chemical Property of Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-2-methyl-, acetate

Chemical Property:

• Vapor Pressure: 8.37E-10mmHg at 25°C
• Boiling Point: 491.5°Cat760mmHg
• PKA: -1.03±0.40(Predicted)
• Flash Point: 251°C
• PSA: 65.07000
• Density: 1.181g/cm³
• LogP: 1.81890
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 319.14197277
• Heavy Atom Count: 23
• Complexity: 450

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CN(CCO1)C(=O)C=CC2=CC(=C(C=C2)OC(=O)C)OC
• Isomeric SMILES: CC1CN(CCO1)C(=O)/C=C/C2=CC(=C(C=C2)OC(=O)C)OC

Technology Process of Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-2-methyl-, acetate

There total 1 articles about Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-2-methyl-, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylmorpholine (27550-90-9) + 4-acetoxy-3-methoxycinnamoyl chloride (50906-12-2) → 2-Methyl-4-(3-methoxy-4-acetoxy-cinnamoyl)-morpholin (19856-72-5)

Guidance literature:

With triethylamine;

Reference yield:

2-Methyl-4-(3-methoxy-4-acetoxy-cinnamoyl)-morpholin (19856-72-5) → 2-Methyl-4-(4-hydroxy-3-methoxy-cinnamoyl)-morpholin (19856-66-7)

Guidance literature:

Multistep reaction; (i) NaOMe, MeOH, (ii) aq. H₂SO₄;

upstream raw materials:

2-methylmorpholine

4-acetoxy-3-methoxycinnamoyl chloride

Downstream raw materials:

2-Methyl-4-(4-hydroxy-3-methoxy-cinnamoyl)-morpholin