2-Methylmorpholine

Base Information

• Chemical Name: 2-Methylmorpholine
• CAS No.: 27550-90-9
• Molecular Formula: C5H11NO
• Molecular Weight: 101.148
• Hs Code.: 2934999090
• Mol file: 27550-90-9.mol

Synonyms:Methylmorpholine;Morpholine, 2-methyl-;

Chemical Property of 2-Methylmorpholine

Chemical Property:

• Vapor Pressure: 0.633mmHg at 25°C
• Boiling Point: 137.1 °C at 760 mmHg
• PKA: 9.01±0.40(Predicted)
• Flash Point: 41.3 °C
• PSA: 21.26000
• Density: 0.891 g/cm³
• LogP: 0.32350
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

90.0%Min ^*data from raw suppliers

2-Methylmorpholine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methylmorpholine

There total 5 articles about 2-Methylmorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.3%

6-methylmorpholin-3-one (127958-63-8) → 2-methylmorpholine (27550-90-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 16h; Inert atmosphere;

Reference yield:

→ 2-methylmorpholine (27550-90-9)

Guidance literature:

With sulfuric acid; at 155 - 165 ℃;

Reference yield:

1-(2-hydroxyethylamino)-2-propanol (6579-55-1) → 2-methylmorpholine (27550-90-9)

Guidance literature:

With sulfuric acid;

DOI:10.1021/ma0612531

upstream raw materials:

sulfuric acid

1-(2-hydroxyethylamino)-2-propanol

6-methylmorpholin-3-one

Downstream raw materials:

N-(p-Nitrobenzyloxycarbonyl)-5-fluorotryptamine

1-(3,4-difluorophenyl)-2-[4-(1-trans-pentenyl)phenyl]acetylene

1-(4-trifluoromethylphenyl)-2-[4-(1-trans-pentenyl)phenyl]acetylene

2-methyl-5-(2-methyl-4-morpholinyl)-3-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one

Refernces

• 1、 -. "INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING". . . Retrieved 2017/09/15.