4-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)BUTANOHYDRAZIDE

Base Information

Chemical Name:4-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)BUTANOHYDRAZIDE
CAS No.:332361-09-8
Molecular Formula:C10H12ClF3N4O
Molecular Weight:296.67700
Hs Code.:
Mol file:332361-09-8.mol

Synonyms:4-(3-Chloro-5-trifluoromethyl-pyridin-2-ylamino)-butyric acid hydrazide;

Suppliers and Price of 4-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)BUTANOHYDRAZIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino}butanohydrazide
5g
$ 7343.00

Matrix Scientific
4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino}butanohydrazide
1g
$ 1836.00

Matrix Scientific
4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino}butanohydrazide
500mg
$ 918.00

Total 3 raw suppliers

Chemical Property of 4-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)BUTANOHYDRAZIDE

Chemical Property:

PSA：80.04000
LogP:3.10000

Purity/Quality:

97% ^*data from raw suppliers

4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino}butanohydrazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)BUTANOHYDRAZIDE

There total 4 articles about 4-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)BUTANOHYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 332361-10-1
methyl 4‐{[3‐chloro‐5‐(trifluoromethyl)pyridin‐2‐yl]amino}butanoate

: 332361-09-8
4-(3-chloro-5-trifluoromethylpyridin-2-ylamino)butyric acid hydrazide

Guidance literature:: With hydrazine hydrate; In methanol; for 2h; Heating;
DOI:10.1021/jm031112e

Reference yield:

t-BuOMe: t-BuOMe

Et3N·HCI salt: Et3N·HCI salt

: 69045-84-7
2,3-dichloro-5-trifluoromethylpyridine

: 56-12-2
4-amino-n-butyric acid

: 332361-10-1
methyl 4‐{[3‐chloro‐5‐(trifluoromethyl)pyridin‐2‐yl]amino}butanoate

: 332361-09-8
4-(3-chloro-5-trifluoromethylpyridin-2-ylamino)butyric acid hydrazide

Guidance literature:: With triethylamine; In methanol; methanolic H₂SO₄(1.9M H₂SO₄in MeOH, 50 ml); dichloromethane; cyclohexane; ethyl acetate;

Reference yield:

: 69045-84-7
2,3-dichloro-5-trifluoromethylpyridine

: 332361-09-8
4-(3-chloro-5-trifluoromethylpyridin-2-ylamino)butyric acid hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: methanol / 3 h / 100 - 104 °C

2: 13.8 g / H₂SO₄ / 1.5 h / Heating

3: 76 percent / aq. NH₂NH₂ / methanol / 2 h / Heating

With sulfuric acid; hydrazine hydrate; In methanol;
DOI:10.1021/jm031112e