Phe-his

Base Information

Chemical Name:Phe-his
CAS No.:33367-37-2
Molecular Formula:C15H18N4O3
Molecular Weight:302.32800
Hs Code.:
DSSTox Substance ID:DTXSID80433453
Nikkaji Number:J88.865F
Wikidata:Q27142495
Metabolomics Workbench ID:78924
Mol file:33367-37-2.mol

Synonyms:His-Phe;histidylphenylalanine;Phe-His;phenylalanylhistidine

Suppliers and Price of Phe-his

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Phe-his

Chemical Property:

PSA：124.59000
LogP:1.63220
XLogP3:-2.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:302.13789045
Heavy Atom Count:22
Complexity:385

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)NC(CC2=CN=CN2)C(=O)O)N
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CC2=CN=CN2)C(=O)O)N

Technology Process of Phe-his

There total 3 articles about Phe-his which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35661-40-6
N-Fmoc L-Phe

: 109425-51-6
Fmoc-His(Trt)-OH

: L-Phe-D-His-OH

: 33367-37-2
L-phenylalanyl-L-histidine

Guidance literature:: Fmoc-His(Trt)-OH; With 1-methyl-1H-imidazole; dmap; at 0 - 20 ℃; for 4h; Green chemistry;

With piperidine; In N,N-dimethyl-formamide; for 0.133333h; Green chemistry;

N-Fmoc L-Phe; Further stages; Green chemistry;
DOI:10.1016/j.tetlet.2019.151058