Fmoc-L-phenylalanine

Base Information

Chemical Name:Fmoc-L-phenylalanine
CAS No.:35661-40-6
Molecular Formula:C24H21NO4
Molecular Weight:387.435
Hs Code.:2924 29 70
European Community (EC) Number:252-661-1
DSSTox Substance ID:DTXSID30951314
Nikkaji Number:J256.551J
Wikidata:Q82929582
ChEMBL ID:CHEMBL357583
Mol file:35661-40-6.mol

Synonyms:fluorenylmethoxycarbonyl-conjugated phenylalanine;Fmoc-Phe;Fmoc-phenylalanine

Suppliers and Price of Fmoc-L-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-L-Phe
500mg
$ 333.00

Usbiological
Fmoc-Phe-OH
50g
$ 333.00

Usbiological
Fmoc-phe
25mg
$ 305.00

Usbiological
Fmoc-L-Phe
1g
$ 252.00

TRC
N-FMOC-L-phenylalanine
250 g
$ 215.00

TRC
N-FMOC-L-phenylalanine
5g
$ 55.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine >98.0%(HPLC)(T)
5g
$ 17.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine >98.0%(HPLC)(T)
25g
$ 53.00

SynQuest Laboratories
Fmoc-Phe-OH 98%
1 kg
$ 671.00

SynQuest Laboratories
Fmoc-Phe-OH 98%
500 g
$ 365.00

Total 164 raw suppliers

Chemical Property of Fmoc-L-phenylalanine

Chemical Property:

Appearance/Colour:white crystalline powder
Vapor Pressure:3.07E-16mmHg at 25°C
Melting Point:180-187 °C(lit.)
Refractive Index:-39.5 ° (C=1, DMF)
Boiling Point:620.1 °C at 760 mmHg
PKA:3.77±0.10(Predicted)
Flash Point:328.8 °C
PSA：75.63000
Density:1.276 g/cm³
LogP:4.61190
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMF (Sparingly, Sonicated), DMSO (Slightly)
XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:387.14705815
Heavy Atom Count:29
Complexity:551

Purity/Quality:

≥98%,≥99%, ^*data from raw suppliers

Fmoc-L-Phe ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 22-24/25-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Uses (Fmoc-Phe-OH) L-Phenylalanine (P319415) derivative, used in the preparation of peptides and deltorphin derivatives. A potential inhibitor of IGF-I and IGF-Binding Protein-5 complex.

Technology Process of Fmoc-L-phenylalanine

There total 54 articles about Fmoc-L-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 129397-81-5
methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-phenylalaninate

: 35661-40-6
N-Fmoc L-Phe

Guidance literature:: With magnesium iodide; In tetrahydrofuran; at 120 ℃; for 0.25h; chemoselective reaction; Inert atmosphere; Microwave irradiation;
DOI:10.1002/chem.201501799

Reference yield: 98.0%

: ethyl (S)-N-α-(fluorenylmethyloxycarbonyl)-phenylalaninate

: 35661-40-6
N-Fmoc L-Phe

Guidance literature:: With magnesium iodide; In tetrahydrofuran; at 120 ℃; for 0.5h; Reagent/catalyst; Solvent; Concentration; chemoselective reaction; Inert atmosphere; Microwave irradiation;
DOI:10.1002/chem.201501799

Reference yield: 96.0%

: (S)-2-(9H-fluoren-9-ylmethoxycarbonyl-amino)-3-phenyl-propionic acid benzyl ester

: 35661-40-6
N-Fmoc L-Phe

Guidance literature:: With magnesium iodide; In tetrahydrofuran; at 120 ℃; for 0.25h; chemoselective reaction; Inert atmosphere; Microwave irradiation;
DOI:10.1002/chem.201501799