Dibenzofuran-1-ol

Base Information

• Chemical Name: Dibenzofuran-1-ol
• CAS No.: 33483-06-6
• Molecular Formula: C12H8O2
• Molecular Weight: 184.194
• Hs Code.: 2932990090
• European Community (EC) Number: 809-942-4
• DSSTox Substance ID: DTXSID50397179
• Nikkaji Number: J1.318.393G
• Wikidata: Q82198294
• Mol file: 33483-06-6.mol

Synonyms:dibenzo[b,d]furan-1-ol;dibenzofuran-1-ol;33483-06-6;1-hydroxydibenzofuran;82493-21-8;Dibenzofuranol;hydroxydibenzofuran;Oprea1_497608;SCHEMBL329069;DTXSID50397179;MFCD00463251;STL328840;AKOS001590334;AS-54898;CS-0036862;EU-0033722;W10863;A930627;{8-oxatricyclo[7.4.0.0?,?]trideca-1(9),2(7),3,5,10,12-hexaen-3-yl}oxidanyl;334970-30-8

Chemical Property of Dibenzofuran-1-ol

Chemical Property:

• PSA: 33.37000
• LogP: 3.29160
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 184.052429494
• Heavy Atom Count: 14
• Complexity: 216

Purity/Quality:

99.3% ^*data from raw suppliers

dibenzofuran-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(C=CC=C3O2)O

Technology Process of Dibenzofuran-1-ol

There total 4 articles about Dibenzofuran-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dioxin (262-12-4) → 1-hydroxydibenzofuran (33483-06-6) + o-Phenoxyphenol (2417-10-9) + 2,2'-dihydroxybiphenyl (1806-29-7)

Guidance literature:

In acetonitrile; at 12 ℃; Mechanism; Irradiation; also 2,3,7,8-tetrachlorodibenzo-1,4-dioxin (TCDD), also with NaBH₄ in aq. MeCN;

DOI:10.1039/c39930000409

Reference yield:

dibenzofuran (132-64-9,214827-48-2) → 2-hydroxydibenzofuran (86-77-1) + 1-hydroxydibenzofuran (33483-06-6)

Guidance literature:

Multi-step reaction with 2 steps

1: oxygen / water / 48 h / 30 °C / pH 8 / Microbiological reaction; Enzymatic reaction

2: pH Ca_. 7

With oxygen; In water;

DOI:10.1002/adsc.201900147

Reference yield:

(1R,2S)-1,2-dihydrodibenzo[b,d]furan-1,2-diol (183256-41-9,404875-12-3,71878-70-1) → 2-hydroxydibenzofuran (86-77-1) + 1-hydroxydibenzofuran (33483-06-6)

Guidance literature:

pH=Ca. 7;

DOI:10.1002/adsc.201900147

upstream raw materials:

dioxin

dibenzofuran

(1R,2S)-1,2-dihydrodibenzo[b,d]furan-1,2-diol

Downstream raw materials:

1-monochlorodibenzofuran

1-(2-chloro-5-trifluoromethylphenylamino)dibenzofuran-4,6-dicarboxylic acid dimethyl ester

1-(3,5-bis-methoxycarbonyl-phenylamino)dibenzofuran-4,6-dicarboxylic acid dimethyl ester

1-(3,5-bis-trifluoromethylphenyl)dibenzofuran-4,6-dicarboxylic acid dimethyl ester