86-77-1Relevant articles and documents
Functional expression of three rieske non-heme iron oxygenases derived from actinomycetes in Rhodococcus species for investigation of their degradation capabilities of dibenzofuran and chlorinated dioxins
Iida, Toshiya,Moteki, Yasuhiro,Nakamura, Kaoru,Taguchi, Katsuhiko,Otagiri, Masato,Asanuma, Miwako,Dohmae, Naoshi,Usami, Ron,Kudo, Toshiaki
, p. 822 - 827 (2009)
The activity of Rieske non-heme iron oxygenases (aromatic hydrocarbon dioxygenases, AhDOs) is important for the bacterial degradation of aromatic pollutants such as polycyclic aromatic hydrocarbons and dioxins. During our analysis of the role of AhDOs in
Preparation method of ganoderma lucidum furan A
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Paragraph 0033-0036; 0039, (2020/09/20)
The invention belongs to the technical field of chemical synthesis, and particularly relates to a preparation method of ganoderma lucidum furan A. According to the preparation method of the ganodermalucidum furan A, a compound shown in a general formula II and a compound shown in a general formula III are subjected to condensation reaction to obtain a compound shown in a general formula I, and the reaction equation is as shown in the specification. According to the technical scheme provided by the invention, a synthetic route which is particularly suitable for amplifying and synthesizing theganoderma lucidum furan A is provided; the selected raw materials, namely dibenzofuran and 2-methyl-2-butenal, are mature chemical products; the method has the advantages of simple process, wide source, low price, mild reaction conditions of the whole reaction route and no special requirements, the obtained intermediate can be directly subjected to subsequent reactions without purification, the route completely overcomes the defects of the synthesis route in the prior art due to the elements, and the method has the prospect of industrial large-scale production.
Chemoenzymatic Synthesis of (-)-Ribisins A and B from Dibenzo[b,d]furan
Boyd, Derek R.,Sharma, Narain D.,McGivern, Christopher J.,Stevenson, Paul J.,Hoering, Patrick,Allen, Christopher C. R.
, (2019/11/29)
cis-Dihydrodiols, derived from monocyclic aromatic compounds, are valuable chiral pool intermediates for the synthesis of cyclic natural products. A drawback of this approach, to the synthesis of polycyclic secondary metabolites, is that additional rings must be annulated. To date, relatively few chiral natural products have been synthesized from polycyclic arene cis-dihydrodiols. Fungal metabolites, (-)-ribisins A and B, have now been obtained by functional group manipulation of a tricyclic arene metabolite, obtained from toluene dioxygenase-catalyzed regioselective and stereoselective cis-dihydroxylations of dibenzo[b,d]furan. The synthetic sequences were marginally shorter than the alternative routes, using monocyclic arene cis-dihydrodiols, and required no carbon-carbon bond-forming reactions.
