2-Methylsulfonyl-4-benzyloxy-pyrimidine

Base Information

Chemical Name:2-Methylsulfonyl-4-benzyloxy-pyrimidine
CAS No.:33489-54-2
Molecular Formula:C12H12N2O3S
Molecular Weight:264.305
Hs Code.:
DSSTox Substance ID:DTXSID00463474
Wikidata:Q82288365

Synonyms:2-methylsulfonyl-4-benzyloxy-pyrimidine;33489-54-2;4-benzyloxy-2-methanesulfonyl-pyrimidine;SCHEMBL3543675;DTXSID00463474;ZSPBHCKOHOVORF-UHFFFAOYSA-N;2-(methylsulfonyl)-4-[(phenylmethyl)oxy]pyrimidine

Suppliers and Price of 2-Methylsulfonyl-4-benzyloxy-pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Methylsulfonyl-4-benzyloxy-pyrimidine

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:264.05686342
Heavy Atom Count:18
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)C1=NC=CC(=N1)OCC2=CC=CC=C2

Technology Process of 2-Methylsulfonyl-4-benzyloxy-pyrimidine

There total 2 articles about 2-Methylsulfonyl-4-benzyloxy-pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 49844-90-8
4-Chloro-2-methylthiopyrimidine

: 100-51-6,185532-71-2
benzyl alcohol

: 33489-54-2
4-benzyloxy-2-methanesulfonylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / 1,4-dioxane; mineral oil / 0.5 h / 100 °C

1.2: 4.5 h / 50 °C

2.1: Oxone / methanol; water; tetrahydrofuran / 0.75 h / 20 °C

With Oxone; sodium hydride; In tetrahydrofuran; 1,4-dioxane; methanol; water; mineral oil;

Reference yield:

: 33489-54-2
4-benzyloxy-2-methanesulfonylpyrimidine

Guidance literature:: Sulfid VI;
DOI:10.1016/S0040-4039(01)97065-0

Reference yield: 52.0%

: C₁₇H₂₇F₃N₄O

: 33489-54-2
4-benzyloxy-2-methanesulfonylpyrimidine

: 193608-09-2
1-[2-t-butyl-6-trifluoromethyl-4-pyrimidinyl]-4-[3-{4-benzyloxy-2-pyrimidinyloxy}propyl]hexahydro-1H-1,4-diazepine

Guidance literature:: C₁₇H₂₇F₃N₄O; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 0.5h;

4-benzyloxy-2-methanesulfonylpyrimidine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 7h;