4-[4-{4-benzyloxy-2-pyrimidinylamino}butyl]-1-[2-t-butyl-6-trifluoromethyl-4-pyrimidinyl]hexahydro-1H-1,4-diazepine

Base Information

Chemical Name:4-[4-{4-benzyloxy-2-pyrimidinylamino}butyl]-1-[2-t-butyl-6-trifluoromethyl-4-pyrimidinyl]hexahydro-1H-1,4-diazepine
CAS No.:193608-04-7
Molecular Formula:C₂₉H₃₈F₃N₇O
Molecular Weight:557.662
Hs Code.:

Synonyms:4-[4-{4-benzyloxy-2-pyrimidinylamino}butyl]-1-[2-t-butyl-6-trifluoromethyl-4-pyrimidinyl]hexahydro-1H-1,4-diazepine

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Chemical Property of 4-[4-{4-benzyloxy-2-pyrimidinylamino}butyl]-1-[2-t-butyl-6-trifluoromethyl-4-pyrimidinyl]hexahydro-1H-1,4-diazepine

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Technology Process of 4-[4-{4-benzyloxy-2-pyrimidinylamino}butyl]-1-[2-t-butyl-6-trifluoromethyl-4-pyrimidinyl]hexahydro-1H-1,4-diazepine

There total 1 articles about 4-[4-{4-benzyloxy-2-pyrimidinylamino}butyl]-1-[2-t-butyl-6-trifluoromethyl-4-pyrimidinyl]hexahydro-1H-1,4-diazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 193611-21-1
1-[2-t-butyl-6-trifluoromethyl-4-pyyrimidinyl]-4-(4-aminobutyl)hexahydro-1H-1,4-diazepine

: 144-62-7,97993-78-7
oxalic acid

: 33489-54-2
4-benzyloxy-2-methanesulfonylpyrimidine

: 193608-04-7
4-[4-{4-benzyloxy-2-pyrimidinylamino}butyl]-1-[2-t-butyl-6-trifluoromethyl-4-pyrimidinyl]hexahydro-1H-1,4-diazepine

Guidance literature:: 1-[2-t-butyl-6-trifluoromethyl-4-pyyrimidinyl]-4-(4-aminobutyl)hexahydro-1H-1,4-diazepine; With sodium hydride; In N,N-dimethyl-formamide; for 1h;

4-benzyloxy-2-methanesulfonylpyrimidine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 72h;

oxalic acid;