Benzylideneisoindolin-3-one

Base Information

Chemical Name:Benzylideneisoindolin-3-one
CAS No.:33608-93-4
Molecular Formula:C15H11NO
Molecular Weight:221.258
Hs Code.:
DSSTox Substance ID:DTXSID80385605

Synonyms:AC1MDNHB;benzylideneisoindolin-3-one;33608-93-4;SCHEMBL19748980;DTXSID80385605

Suppliers and Price of Benzylideneisoindolin-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Benzylideneisoindolin-3-one

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:221.084063974
Heavy Atom Count:17
Complexity:328

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C=C2C3=CC=CC=C3C(=O)N2

Technology Process of Benzylideneisoindolin-3-one

There total 20 articles about Benzylideneisoindolin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 20871-31-2
2,3-dihydro-3-hydroxy-3-(phenylmethyl)-1H-isoindol-1-one

: 33608-93-4
(E)-2,3-dihydro-3-phenylmethylene-1H-isoindol-1-one

Guidance literature:: With sulfuric acid; In dichloromethane; at 0 - 20 ℃; stereoselective reaction;
DOI:10.1016/j.tetlet.2010.07.017

Reference yield: 79.6%

: C₂₁H₁₇NO₂

: 33608-93-4
(E)-2,3-dihydro-3-phenylmethylene-1H-isoindol-1-one

: 40523-32-8
3-(phenylmethylene)isoindol-1-one

Guidance literature:: With tributyl-amine; tris(2,2,2-trifluoroethyl)phosphite; bis(trimethylsilylmethyl)(cycloocta-1,5-diene)palladium(II); In acetonitrile; at 80 ℃; for 2h; Time; stereoselective reaction; Glovebox; Sealed tube; Inert atmosphere;
DOI:10.1021/jacs.6b08932

Reference yield: 75.0%

: 891194-28-8
methyl 1-oxo-1,3-dihydro-2H-isoindole-2-carboxylate

: 100-52-7
benzaldehyde

: 33608-93-4
(E)-2,3-dihydro-3-phenylmethylene-1H-isoindol-1-one

: 40523-32-8
3-(phenylmethylene)isoindol-1-one

Guidance literature:: methyl 1-oxo-1,3-dihydro-2H-isoindole-2-carboxylate; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

benzaldehyde; In N,N-dimethyl-formamide; for 9h; Heating;
DOI:10.1055/s-2006-926413