1-Methyl-1,2-dihydropyridine

Base Information

• Chemical Name: 1-Methyl-1,2-dihydropyridine
• CAS No.: 33707-38-9
• Molecular Formula: C6H9N
• Molecular Weight: 95.1442
• DSSTox Substance ID: DTXSID70502748
• Nikkaji Number: J1.081.795A
• Wikidata: Q82356030
• Mol file: 33707-38-9.mol

Synonyms:1-methyl-1,2-dihydropyridine;N-METHYLPYRIDINE;33707-38-9;N-methypyridine;1-methyl-1,2-dihydro-pyridine;DTXSID70502748;HZONRRHNQILCNO-UHFFFAOYSA-N

Chemical Property of 1-Methyl-1,2-dihydropyridine

Chemical Property:

• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 95.073499291
• Heavy Atom Count: 7
• Complexity: 103

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CC=CC=C1

Technology Process of 1-Methyl-1,2-dihydropyridine

There total 2 articles about 1-Methyl-1,2-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methyl pyridinium iodide (930-73-4,61734-40-5) → N-methyl-1,2-dihydropyridine (33707-38-9) + N-methyl-3,4-didehydropiperidine (694-55-3)

Guidance literature:

With sodium hydroxide; sodium tetrahydroborate; In methanol; hexane; water; at 15 ℃; for 0.1h; Title compound not separated from byproducts;

DOI:10.1016/0223-5234(87)90166-8

Reference yield:

1-methyl pyridinium iodide (930-73-4,61734-40-5) → N-methyl-1,2-dihydropyridine (33707-38-9) + N-methyl-1,4-dihydropyridine (33666-44-3)

Guidance literature:

With sodium hydrogen telluride; In ethanol; Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature; pH 10-11;

DOI:10.1016/S0040-4039(00)89225-4

Reference yield: 51.0%

N-methyl-1,2-dihydropyridine (33707-38-9) + phenylsulfonyl azide (938-10-3) → 2-methyl-7-benzenesulfonyl-2,7-diazabicyclo<4.1.0>hept-4-ene (99344-30-6)

Guidance literature:

In diethyl ether; at 25 ℃; for 0.25h;

upstream raw materials:

1-methyl pyridinium iodide

Downstream raw materials:

2-methyl-7-benzenesulfonyl-2,7-diazabicyclo<4.1.0>hept-4-ene

N-methyl-3,4-didehydropiperidine

methylamine

N-(1-methylpiperidin-2-ylidene)benzenesulfonamide