Methylamine

Base Information

• Chemical Name: Methylamine
• CAS No.: 74-89-5
• Deprecated CAS: 119775-09-6,42939-70-8,85404-17-7,1391413-98-1,2421217-09-4,1391413-98-1,42939-70-8,85404-17-7
• Molecular Formula: CH5N
• Molecular Weight: 31.0574
• Hs Code.: 2921.11 Oral rat LD50: 100 mg/kg
• European Community (EC) Number: 200-820-0
• ICSC Number: 0178
• UN Number: 1061,1235
• UNII: BSF23SJ79E
• DSSTox Substance ID: DTXSID7025683
• Nikkaji Number: J1.431A,J768.885G
• Wikipedia: Methylamine
• Wikidata: Q409304,Q83060774,Q83070807
• Metabolomics Workbench ID: 75084
• ChEMBL ID: CHEMBL43280
• Mol file: 74-89-5.mol

Synonyms:aminomethane;methylamine;methylamine bisulfite;methylamine hydride;methylamine hydrobromide;methylamine hydrochloride;methylamine hydrochloride, 14C-labeled;methylamine hydrofluoride;methylamine hydrogen cyanide;methylamine hydroiodide;methylamine ion (1-);methylamine nitrate;methylamine perchlorate;methylamine sulfate (1:1);methylamine sulfate (2:1);methylamine, 13C-labeled;methylamine, 14C-labeled;methylamine, 15N-labeled;methylamine, cesium salt;methylamine, monopotassium salt;methylamine, monosodium salt;methylammonium;methylammonium ion;monomethylamine;monomethylammonium ion

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Chemical Property of Methylamine

Chemical Property:

• Appearance/Colour: colourless gas
• Vapor Pressure: 3970mmHg at 25°C
• Melting Point: -93 °C
• Refractive Index: 1.351
• Boiling Point: -6.5 °C
• Flash Point: 61°F
• PSA: 26.02000
• Density: 0.70 g/cm³
• LogP: 0.27520
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 31.042199164
• Heavy Atom Count: 2
• Complexity: 2
• Transport DOT Label: Flammable Gas

Purity/Quality:

Safty Information:

• Pictogram(s): F+, Xn, C, F, T
• Hazard Codes: Xn:Harmful;;
• Statements: R12:; R20:; R37/38:; R41:
• Safety Statements: S16:; S26:; S29:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CN
• Inhalation Risk: A harmful concentration of this gas in the air will be reached very quickly on loss of containment.
• Effects of Short Term Exposure: The substance is corrosive to the eyes and respiratory tract. Inhalation of high levels may cause lung oedema. The effects may be delayed. Medical observation is indicated. Rapid evaporation of the liquid may cause frostbite.

Technology Process of Methylamine

There total 1065 articles about Methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

trimethylaluminum (75-24-1) + benzyl-methyl-amine (103-67-3) → ethylbenzene (100-41-4,27536-89-6) + 1,1'-(1,2-ethanediyl)bisbenzene (103-29-7) + toluene (108-88-3,15644-74-3,16713-13-6) + methylamine (74-89-5)

Guidance literature:

In benzene; for 50h; Irradiation;

DOI:10.1246/cl.1982.1633

Reference yield:

chloropicrin (76-06-2) → dichloroformoxime (1794-86-1) + N-Methylhydroxylamine (593-77-1) + trichloronitrosomethane (3711-49-7) + methylamine (74-89-5)

Guidance literature:

Bei der elektrolytischen Reduktion entstehen je nach den Bedingungen wechselnde Menge;

Reference yield:

4,N-dimethyl-2,6,N-trinitro-aniline (62323-65-3) + furan-2,3,5(4H)-trione pyridine (1:1) → 2,6-dinitro-p-cresol (609-93-8) + methylamine (74-89-5)

Guidance literature:

upstream raw materials:

acetamide

Succinimide

formaldehyd

methanol

Downstream raw materials:

2-(N-methylamino)pyridine

4-methyl-1,2,4-triazoline-5-thione

2,3-dihydro-1H-1,2,4-triazole-3-thione

N-methyl-1,2,4-thiadiazol-5-amine

Refernces

• 1、 Shaw,Walker. "-". . p. 3683,3684,3685. Retrieved 1957.
• 2、 Schuerc, C.,Huntress, E. H.. "". . p. 2233 - 2237. Retrieved 1949.
• 3、 Jodkowski, Jerzy T.,Ratajczak, Emil,Fagerstroem, Kjell,Lund, Anders,Stothard, Nigel D.,et al.. "Kinetics of the cross reaction between amidogen and methyl radicals". . p. 63 - 71. Retrieved 1995.
• 4、 Pang, Shuping,Zhou, Yuanyuan,Wang, Zaiwei,Yang, Mengjin,Krause, Amanda R.,Zhou, Zhongmin,Zhu, Kai,Padture, Nitin P.,Cui, Guanglei. "Transformative Evolution of Organolead Triiodide Perovskite Thin Films from Strong Room-Temperature Solid-Gas Interaction between HPbI3-CH3NH2 Precursor Pair". . p. 750 - 753. Retrieved 2016.
• 5、 Aston,Gittler. "". . p. 3175. Retrieved 1955.
• 6、 Lagerkvist. "-". . p. 543,545. Retrieved 1950.
• 7、 Ansari, Sara,Khorshidi, Alireza,Shariati, Shahab. "Synthesis of Ultrafine Silver Nanoparticles on the Surface of Fe3O4@SiO2@KIT-6-NH2 Nanocomposite and Their Application as a Highly Efficient and Reusable Catalyst for Reduction of Nitrofurazone and Aromatic Nitro Compounds Under Mild Conditions". . p. 410 - 418. Retrieved 2019.
• 8、 Malinak, Steven M.,Simeonov, Anton M.,Mosier, Patrick E.,McKenna, Charles E.,Coucouvanis, Dimitri. "Catalytic reduction of cis-dimethyldiazene by the [MoFe3S4]3+ clusters. The four-electron reduction of a N = N bond by a nitrogenase-relevant cluster and implications for the function of nitrogenase". . p. 1662 - 1667. Retrieved 1997.
• 9、 Rooney, Conor L.,Wu, Yueshen,Tao, Zixu,Wang, Hailiang. "Electrochemical Reductive N-Methylation with CO2Enabled by a Molecular Catalyst". supporting information. p. 19983 - 19991. Retrieved 2021/12/01.
• 10、 Zou, Zhijuan,Jiang, Yaya,Song, Kunpeng. "Pd Nanoparticles Assembled on Metalporphyrin-Based Microporous Organic Polymer as Efficient Catalyst for Tandem Dehydrogenation of Ammonia Borane and Hydrogenation of Nitro Compounds". . p. 1277 - 1286. Retrieved 2019/11/20.