3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine

Base Information

Chemical Name:3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine
CAS No.:337368-14-6
Molecular Formula:C18H20N2O5
Molecular Weight:344.367
Hs Code.:
DSSTox Substance ID:DTXSID70461063
Wikidata:Q82285301
Mol file:337368-14-6.mol

Synonyms:3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine;337368-14-6;(2S)-3-(phenylmethoxyamino)-2-(phenylmethoxycarbonylamino)propanoic acid;DTXSID70461063;AKOS027447790;J-019309

Suppliers and Price of 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine
500mg
$ 1230.00

American Custom Chemicals Corporation
3-((BENZYLOXY)AMINO)-N-((BENZYLOXY)CARBONYL)-L-ALANINE 95.00%
500MG
$ 1871.10

American Custom Chemicals Corporation
3-((BENZYLOXY)AMINO)-N-((BENZYLOXY)CARBONYL)-L-ALANINE 95.00%
50MG
$ 315.00

Total 2 raw suppliers

Chemical Property of 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine

Chemical Property:

Melting Point:73-75 °C(Solv: ethyl acetate (141-78-6))
PKA:12.72±0.46(Predicted)
PSA：96.89000
Density:1.268±0.06 g/cm3(Predicted)
LogP:2.86920
Solubility.:Acetone, Chloroform, Dichloromethane
XLogP3:-0.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:344.13722174
Heavy Atom Count:25
Complexity:406

Purity/Quality:

95% ^*data from raw suppliers

3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NC(CNOCC2=CC=CC=C2)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)N[C@@H](CNOCC2=CC=CC=C2)C(=O)O

Technology Process of 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine

There total 4 articles about 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 71404-99-4,1246814-58-3
(S)-[1-(phenylmethyloxy)-2-oxo-3-azetidinyl]carbamic acid phenylmethyl ester

: 337368-14-6,96521-76-5
(S)-3-[(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃;
DOI:10.1002/ejoc.200400508

Reference yield:

: 1145-80-8
N-(benzyloxycarbonyl)-L-serine

: 337368-14-6,96521-76-5
(S)-3-[(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / DCC / acetonitrile / 0 - 20 °C

2: 87 percent / PPh₃; Et₃N / acetonitrile; CCl₄ / 24 h / 20 °C

3: 99 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 20 °C

With lithium hydroxide; triethylamine; dicyclohexyl-carbodiimide; triphenylphosphine; In tetrahydrofuran; tetrachloromethane; water; acetonitrile;
DOI:10.1002/ejoc.200400508

Reference yield:

: 622-33-3
N-benzyloxyamine

: 337368-14-6,96521-76-5
(S)-3-[(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / DCC / acetonitrile / 0 - 20 °C

2: 87 percent / PPh₃; Et₃N / acetonitrile; CCl₄ / 24 h / 20 °C

3: 99 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 20 °C

With lithium hydroxide; triethylamine; dicyclohexyl-carbodiimide; triphenylphosphine; In tetrahydrofuran; tetrachloromethane; water; acetonitrile;
DOI:10.1002/ejoc.200400508