Hydroxy CyclophosphaMide O-MethyloxiMe

Base Information

Chemical Name:Hydroxy CyclophosphaMide O-MethyloxiMe
CAS No.:343967-21-5
Molecular Formula:C8H18Cl2N3O3P
Molecular Weight:306.12700
Hs Code.:
Mol file:343967-21-5.mol

Synonyms:Hydroxy Cyclophosphamide O-Methyloxime;aldophosphamide O-methyloxime;(Z)-aldophosphamide O-methyl oxime;

Suppliers and Price of Hydroxy CyclophosphaMide O-MethyloxiMe

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Hydroxy Cyclophosphamide O-Methyloxime
5mg
$ 496.00

TRC
HydroxyCyclophosphamideO-Methyloxime
5mg
$ 215.00

Total 1 raw suppliers

Chemical Property of Hydroxy CyclophosphaMide O-MethyloxiMe

Chemical Property:

Melting Point:75 - 78°C
PSA：86.96000
LogP:2.57200
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), DMSO (Slightly)

Purity/Quality:: Hydroxy Cyclophosphamide O-Methyloxime ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N,N-Bis(2-chloroethyl-phosphorodiamidic Acid 3-(Methoxyimino)propyl Ester is a derivative of 4-Hydroperoxy Cyclophosphamide (H714675), a metabolite of Cyclophosphamide. Antineoplastic; bone marrow purging agent.

Technology Process of Hydroxy CyclophosphaMide O-MethyloxiMe

There total 5 articles about Hydroxy CyclophosphaMide O-MethyloxiMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39800-16-3,56922-83-9,61903-31-9,62435-42-1,146566-40-7
trans-4-hydroperoxycyclophosphamide

: 343967-21-5,82084-80-8
aldophosphamide O-methyloxime

Guidance literature:: Multi-step reaction with 2 steps

1: Ph₃P / 0.08 h

2: NaOH / D₂O / 0.17 h / lutidine buffer, pH 7.4

With sodium hydroxide; triphenylphosphine; In water-d2;
DOI:10.1002/jps.2600710417

Reference yield:

: 593-56-6
N-methoxylamine hydrochloride

: 61903-30-8,88852-78-2,40277-05-2,61903-29-5,88852-77-1
trans-4-hydroxycyclophosphamide

: 343967-21-5,82084-80-8
aldophosphamide O-methyloxime

: 82084-80-8
(E)-aldophosphamide O-methyl oxime

Guidance literature:: With sodium hydroxide; for 0.166667h; Title compound not separated from byproducts; lutidine buffer, pH 7.4;
DOI:10.1002/jps.2600710417

Reference yield:

: 593-56-6
N-methoxylamine hydrochloride

: 39800-16-3,146566-40-7
4-hydroperoxycyclophosphamide

: 343967-21-5,82084-80-8
aldophosphamide O-methyloxime

: 82084-80-8
(E)-aldophosphamide O-methyl oxime

Guidance literature:: With sodium hydroxide; In water; for 24h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;
DOI:10.1002/jps.2600710417