4-PHENYL-CYCLOHEXANECARBOXYLIC ACID

Base Information

• Chemical Name: 4-PHENYL-CYCLOHEXANECARBOXYLIC ACID
• CAS No.: 7494-76-0
• Molecular Formula: C13H16O2
• Molecular Weight: 204.269
• Hs Code.: 2916399090
• Mol file: 7494-76-0.mol

Synonyms:4-Phenyl-1-cyclohexanamine;4-phenylcyclohexanamine;4-cis-phenylcyclohexylamine;cis-4-phenylcyclohexylamine;CYCLOHEXANAMINE,4-PHENYL;4-Phenyl-hexahydrobenzoesaeure;1-Amino-4-phenylcyclohexane;4-Phenyl-cyclohexancarbonsaeure;trans-4-phenylcyclohexylamine;trans-4-phenylcyclohexane carboxylic acid;4-phenyl-cyclohexanecarboxylic acid;4-phenyl-cyclohexyl amine;

Chemical Property of 4-PHENYL-CYCLOHEXANECARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 8.23E-06mmHg at 25°C
• Boiling Point: 360°C at 760 mmHg
• Flash Point: 167.3°C
• PSA: 37.30000
• Density: 1.116g/cm³
• LogP: 3.04500
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

trans-4-PhenylcyclohexanecarboxylicAcid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-PHENYL-CYCLOHEXANECARBOXYLIC ACID

There total 14 articles about 4-PHENYL-CYCLOHEXANECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

cyclohexene-1-carboxylic acid (636-82-8) → trans-4-phenylcyclohexane carboxylic acid (7494-76-0)

Guidance literature:

With hydrogenchloride; AlCl₃; In benzene;

Reference yield:

→ trans-4-phenylcyclohexane carboxylic acid (7494-76-0)

Guidance literature:

With hydrogenchloride; at 170 - 180 ℃; low-melting form;

Reference yield:

→ trans-4-phenylcyclohexane carboxylic acid (7494-76-0)

Guidance literature:

With hydrogenchloride; at 180 ℃; high-melting form;

upstream raw materials:

pentan-1-ol

biphenyl-4-carboxylic acid

4-phenylcyclohexane-1-carbonitrile

acetic acid

Downstream raw materials:

benzoic acid

1-hydroxy-4-phenyl-cyclohexanecarboxylic acid

N-methoxy-N-methyl-4-phenylcyclohexanecarboxamide

C₂₅H₂₉N₃O

Refernces

• 1、 -. "Succinate derivative compounds useful as cysteine protease inhibitors". . . Retrieved 2008/06/13.