2-[[(3a,5b,7b,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-Ethanesulfonic acid

Base Information

• Chemical Name: 2-[[(3a,5b,7b,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-Ethanesulfonic acid
• CAS No.: 86386-60-9
• Molecular Formula: C₂₆H₄₅NO₇S
• Molecular Weight: 515.712
• Mol file: 86386-60-9.mol

Synonyms:

Chemical Property of 2-[[(3a,5b,7b,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-Ethanesulfonic acid

Chemical Property:

• PSA: 152.54000
• LogP: 3.83980

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[[(3a,5b,7b,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-Ethanesulfonic acid

There total 4 articles about 2-[[(3a,5b,7b,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-Ethanesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

Tau (107-35-7) + ursocholic acid (2955-27-3) → tauroursocholic acid (86386-60-9)

Guidance literature:

With 4-methyl-morpholine; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; triethylamine; In ethanol; for 0.05h; Irradiation;

DOI:10.1016/0968-0896(96)00084-3

Reference yield:

→ Taurocholsaeure (81-24-3,32747-06-1,59005-70-8,86386-60-9,90082-01-2,90082-04-5,107656-89-3)

Guidance literature:

Cholsaeure, 1) Taurin, /BRN= 533048/, NEt3, 2) methanol. NaOH;

Reference yield:

tauro-3α,12α-dihydroxy-7-oxo-5β-cholenoic acid (67460-69-9) → tauroursocholic acid (86386-60-9)

Guidance literature:

With potassium phosphate; D-glucose; NADP; diothiothreitol; In water; glucose dehydrogenase, 7β-hydroxysteroid dehydrogenase;

DOI:10.1021/jo00054a039

upstream raw materials:

tauro-3α,12α-dihydroxy-7-oxo-5β-cholenoic acid

Tau

ursocholic acid

Taurocholic acid

Refernces

• 1、 Bovara, Roberto,Canzi, Enrica,Carrea, Giacomo,Pilotti, Alessandra,Riva, Sergio. "Enzymatic α/β-Inversion of the C-7 Hydroxyl of Steroids". . p. 499 - 501. Retrieved 2007/10/02.