Ethyl 3-amino-4-(cyclohexylamino)benzoate

Base Information Edit

Chemical Name:Ethyl 3-amino-4-(cyclohexylamino)benzoate
CAS No.:347174-05-4
Molecular Formula:C15H22N2O2
Molecular Weight:262.352
Hs Code.:2922499990
European Community (EC) Number:803-483-3
Nikkaji Number:J1.937.012G
Wikidata:Q100614022
ChEMBL ID:CHEMBL3633556
Mol file:347174-05-4.mol

Synonyms:ferrostatin-1

Suppliers and Price of Ethyl 3-amino-4-(cyclohexylamino)benzoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ferrostatin1
10mg
$ 90.00

Sigma-Aldrich
Ferrostatin-1 ≥95% (HPLC)
5mg
$ 61.50

Sigma-Aldrich
Ferrostatin-1 ≥95% (HPLC)
25mg
$ 250.00

Matrix Scientific
Ethyl 3-amino-4-(cyclohexylamino)benzoate
500mg
$ 215.00

Matrix Scientific
Ethyl 3-amino-4-(cyclohexylamino)benzoate
2.500g
$ 510.00

DC Chemicals
Ferrostatin-1(Fer-1) >98%
1 g
$ 1350.00

DC Chemicals
Ferrostatin-1(Fer-1) >98%
100 mg
$ 400.00

CSNpharm
Ferrostatin-1
5mg
$ 61.00

CSNpharm
Ferrostatin-1
10mg
$ 92.00

Crysdot
Ferrostatin-1 95+%
25mg
$ 252.00

Total 22 raw suppliers

Chemical Property of Ethyl 3-amino-4-(cyclohexylamino)benzoate Edit

Chemical Property:

Boiling Point:437.3±35.0 °C(Predicted)
PKA:4.78±0.11(Predicted)
PSA：64.35000
Density:1.150±0.06 g/cm3(Predicted)
LogP:3.84430
Storage Temp.:2-8°C
Solubility.:DMSO: soluble10mg/mL, clear
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:262.168127949
Heavy Atom Count:19
Complexity:290

Purity/Quality:

99% ^*data from raw suppliers

Ferrostatin1 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N
Description Ferrostatin-1 (347174-05-4) inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death.1?Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices.1?Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells.2?Ferrostatin-1 inhibits oxidative lipid damage and cell death in diverse disease models3 and prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4.
Uses Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis.

Technology Process of Ethyl 3-amino-4-(cyclohexylamino)benzoate

There total 12 articles about Ethyl 3-amino-4-(cyclohexylamino)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%