2-Methyl-5-phenylfuran

Base Information

• Chemical Name: 2-Methyl-5-phenylfuran
• CAS No.: 34721-89-6
• Molecular Formula: C11H10O
• Molecular Weight: 158.2
• DSSTox Substance ID: DTXSID80456086
• Nikkaji Number: J730.555I
• Wikidata: Q82278295
• Mol file: 34721-89-6.mol

Synonyms:2-methyl-5-phenylfuran;2-methyl-5-phenyl-furan;34721-89-6;Furan, 2-methyl-5-phenyl-;5-phenyl-2-methylfuran;2-Phenyl-5-methylfuran;SCHEMBL2199459;PQYQNYWJAXBMEL-UHFFFAOYSA-;DTXSID80456086;AKOS015904865;InChI=1/C11H10O/c1-9-7-8-11(12-9)10-5-3-2-4-6-10/h2-8H,1H3

Chemical Property of 2-Methyl-5-phenylfuran

Chemical Property:

• Melting Point: 42 °C
• Boiling Point: 229.5±9.0 °C(Predicted)
• PSA: 13.14000
• Density: 1.028±0.06 g/cm3(Predicted)
• LogP: 3.25500
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 158.073164938
• Heavy Atom Count: 12
• Complexity: 138

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(O1)C2=CC=CC=C2

Technology Process of 2-Methyl-5-phenylfuran

There total 84 articles about 2-Methyl-5-phenylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(penta-1,4-diynyl)benzene (6088-96-6) → 2-methyl-5-phenyl-furan (34721-89-6)

Guidance literature:

With water; PtCl₄-CO; In tetrahydrofuran; at 80 ℃; for 3h; under 1034.3 Torr;

DOI:10.1021/jo961740m

Reference yield: 99.0%

4-bromo-1-phenylpent-4-en-1-one (56418-13-4) → 2-methyl-5-phenyl-furan (34721-89-6)

Guidance literature:

With copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin; caesium carbonate; In 1,4-dioxane; for 5h; Reflux;

DOI:10.1016/j.tetlet.2010.05.040

Reference yield: 98.0%

5-phenylpent-4-yne-2,3-diol (958230-58-5) → 2-methyl-5-phenyl-furan (34721-89-6)

Guidance literature:

With silver(I) nitrate on silica gel; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/j.tetlet.2007.08.102

upstream raw materials:

4-chloro-1-phenyl-pent-3-en-1-one

acetic anhydride

1-phenylpentane-1,4-dione

2-methylfuran

Downstream raw materials:

3-phenyl-2-cyclopenten-1-one

tetrahydro-2-methyl-5-phenylfuran

3-(5-methyl-3-phenyl-1,4,2-dioxazol-5-yl)acrylophenone

4a,7a-dihydro-7a-methyl-3,6-diphenylfuro<3,2-e>-1,4-2-dioxazine