Benzo[b]thiophen-3-amine, 5-nitro-

Base Information

Chemical Name:Benzo[b]thiophen-3-amine, 5-nitro-
CAS No.:348617-86-7
Molecular Formula:C₈H₆N₂O₂S
Molecular Weight:194.214
Hs Code.:
Mol file:348617-86-7.mol

Synonyms:3-amino-5-nitrobenzo[b]thiophene;5-Nitro-benzo[b]thiophen-3-ylamine;

Suppliers and Price of Benzo[b]thiophen-3-amine, 5-nitro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Nitrobenzo[b]thiophen-3-amine 97%
1g
$ 842.00

Alichem
5-Nitrobenzo[b]thiophen-3-amine
1g
$ 711.36

Total 2 raw suppliers

Chemical Property of Benzo[b]thiophen-3-amine, 5-nitro-

Chemical Property:

Melting Point:155 - 158 °C
PSA：100.08000
LogP:3.49610

Purity/Quality:

97% ^*data from raw suppliers

5-Nitrobenzo[b]thiophen-3-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzo[b]thiophen-3-amine, 5-nitro-

There total 2 articles about Benzo[b]thiophen-3-amine, 5-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 34674-75-4
3-amino-5-nitrobenzo-[b]-thiophene-2-carboxylic acid methyl ester

: 348617-86-7
5-nitrobenzo[b]thiophen-3-amine

Guidance literature:: With 1-methyl-piperazine; In 1-methyl-pyrrolidin-2-one; at 180 ℃; for 2h;
DOI:10.1002/jhet.5570390425

Reference yield:

: 109-01-3
1-methyl-piperazine

: 34674-75-4
3-amino-5-nitrobenzo-[b]-thiophene-2-carboxylic acid methyl ester

: 348617-86-7
5-nitrobenzo[b]thiophen-3-amine

Guidance literature:: In 1-methyl-pyrrolidin-2-one; diethyl ether; hexane; ethyl acetate;

Reference yield:

: 348617-86-7
5-nitrobenzo[b]thiophen-3-amine

: 348618-04-2
4-[(3-bromophenyl)amino]-8-nitro[1]benzothieno[3,2-b]pyridine-3-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: toluene / 2 h / Heating

1.2: 46 percent / Dowtherm-A / 4 h / Heating

2.1: 68 percent / POCl₃ / 3 h / Heating

3.1: 66 percent / pyridine hydrochloride / 2-ethoxy-ethanol / 4 h / Heating

With pyridine hydrochloride; trichlorophosphate; In 2-ethoxy-ethanol; toluene;
DOI:10.1002/jhet.5570390425