348618-04-2

Upstream product

• 348617-87-8 1,4-dihydro-8-nitro-4-oxo-[1]benzothieno[3,2-b]pyridine-3-carbonitrile 
• 348617-86-7 5-nitrobenzo[b]thiophen-3-amine 
• 34674-75-4 3-amino-5-nitrobenzo-[b]-thiophene-2-carboxylic acid methyl ester 
• 591-19-5 m-Bromoaniline 
• 348617-88-9 4-chloro-8-nitro-[1]benzothieno[3,2-b]pyridine-3-carbonitrile 

Downstream Products

• 348618-05-3 8-amino-4-[(3-bromophenyl)amino]-[1]benzothieno[3,2-b]pyridine-3-carbonitrile 

Relevant academic research and scientific papers

Preparation of a series of benzothieno[3,2-b]pyridine-3-carbonitriles and benzofuro[3,2-b]pyridine-3-carbonitriles

New and shorter routes to the benzothieno[3,2-b]pyridine-3-carbonitrile and benzofuro[3,2-b]pyridine-3-carbonitrile ring systems are reported. These heterocycles may function as new templates for kinase inhibitors.

Tricyclic protein kinase inhibitors

This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyro sine kinase and are antiproliferative agents.