N-(2-NITROBENZENESULFONYL)-1,4-DIAMINOBUTANE HYDROCHLORIDE

Base Information

• Chemical Name: N-(2-NITROBENZENESULFONYL)-1,4-DIAMINOBUTANE HYDROCHLORIDE
• CAS No.: 349553-74-8
• Molecular Formula: C10H15N3O4S.ClH
• Molecular Weight: 309.77000
• Mol file: 349553-74-8.mol

Synonyms:N-NOSYL-1,4-DIAMINOBUTANE HYDROCHLORIDE;NS-DAB HCL;

Chemical Property of N-(2-NITROBENZENESULFONYL)-1,4-DIAMINOBUTANE HYDROCHLORIDE

Chemical Property:

• PSA: 126.39000
• LogP: 4.10920

Purity/Quality:

98%Min ^*data from raw suppliers

Ns-DAB*HCl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-NITROBENZENESULFONYL)-1,4-DIAMINOBUTANE HYDROCHLORIDE

There total 3 articles about N-(2-NITROBENZENESULFONYL)-1,4-DIAMINOBUTANE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-(4-azido-butyl)-2-nitro-benzenesulfonamide → N-(2-nitrobenzenesulfonyl)-1,4-diaminobutane hydrochloride (349553-74-8)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; water; at 20 ℃; for 24h;

DOI:10.1016/S0040-4039(01)00282-9

Reference yield: 55.0%

2-Nitrobenzenesulfonyl chloride (1694-92-4) + 1,4-diaminobutane (110-60-1) → N-(2-nitrobenzenesulfonyl)-1,4-diaminobutane hydrochloride (349553-74-8)

Guidance literature:

With 4-methyl-morpholine; In tetrahydrofuran; for 2h;

DOI:10.1081/SCC-120002114

Reference yield:

1-(2-nitrobenzenesulfonyl)amino-4-(tert-butoxycarbonyl)aminobutane (211512-15-1) → N-(2-nitrobenzenesulfonyl)-1,4-diaminobutane hydrochloride (349553-74-8)

Guidance literature:

With hydrogenchloride; In methanol;

DOI:10.1021/jo0507486

upstream raw materials:

2-Nitrobenzenesulfonyl chloride

1,4-diaminobutane

1-(2-nitrobenzenesulfonyl)amino-4-(tert-butoxycarbonyl)aminobutane