2-Oxazolidinone, 3-(2-(4-(8-fluoro-2-methyl-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl)ethyl)-, (+-)-

Base Information

Chemical Name:2-Oxazolidinone, 3-(2-(4-(8-fluoro-2-methyl-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl)ethyl)-, (+-)-
CAS No.:59849-49-9
Molecular Formula:C24H28FN3O2S
Molecular Weight:441.5614
Hs Code.:
DSSTox Substance ID:DTXSID80975247

Synonyms:59849-49-9;2-Oxazolidinone, 3-(2-(4-(8-fluoro-2-methyl-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl)ethyl)-, (+-)-;SCHEMBL11610695;DTXSID80975247;PUILADRSZIIQMY-UHFFFAOYSA-N;LS-100579;3-{2-[4-(8-fluoro-10,11-dihydro-2-methyl-dibenzo [b,f]thiepin-10-yl)-1-piperazinyl]-ethyl}-2-oxazolidinone;3-{2-[4-(8-Fluoro-2-methyl-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazin-1-yl]ethyl}-1,3-oxazolidin-2-one;racemic 3-{2-[4-(8-fluoro-10,11-dihydro-2-methyl-dibenzo[b,f]thiepin-10-yl)-1-piperazinyl]-ethyl }-2-oxazolidinone;racemic 3-{2-[4-(8-fluoro-10,11-dihydro-2-methyl-dibenzo[b,f]thiepin-10-yl)-1-piperazinyl]-ethyl}-2-oxazolidinone;racemic 3-{2-[4-(8-fluoro-10,11-dihydro-2-methyldibenzo[b,f]thiepin-10-yl)-1-piperazinyl]-ethyl}-2-oxazolidinone

Suppliers and Price of 2-Oxazolidinone, 3-(2-(4-(8-fluoro-2-methyl-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl)ethyl)-, (+-)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Oxazolidinone, 3-(2-(4-(8-fluoro-2-methyl-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl)ethyl)-, (+-)-

Chemical Property:

Vapor Pressure:1.49E-14mmHg at 25°C
Boiling Point:604.3°C at 760 mmHg
Flash Point:319.3°C
Density:1.272g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:441.18862648
Heavy Atom Count:31
Complexity:632

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)SC3=C(C=C(C=C3)F)C(C2)N4CCN(CC4)CCN5CCOC5=O

Technology Process of 2-Oxazolidinone, 3-(2-(4-(8-fluoro-2-methyl-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl)ethyl)-, (+-)-

There total 6 articles about 2-Oxazolidinone, 3-(2-(4-(8-fluoro-2-methyl-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl)ethyl)-, (+-)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.3%

: 59849-49-9
(-)-(R)-3-<2-<4-(8-Fluor-10,11-dihydro-2-methyldibenzo thiepin-10-yl)-1-piperazinyl>-aethyl>-2-oxazolidinon

: 59905-24-7
3-{2-[4-((S)-8-fluoro-2-methyl-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-piperazin-1-yl]-ethyl}-oxazolidin-2-one

Guidance literature:

Reference yield:

: 52548-37-5
3-[2-(4-benzyl-piperazin-1-yl)-ethyl]-oxazolidin-2-one

: 59849-49-9
(-)-(R)-3-<2-<4-(8-Fluor-10,11-dihydro-2-methyldibenzo thiepin-10-yl)-1-piperazinyl>-aethyl>-2-oxazolidinon

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd-C / methanol / 16 h / 50 °C

2: CHCl₃ / 42 h / Heating

With hydrogen; palladium on activated charcoal; In methanol; chloroform;
DOI:10.1002/hlca.19760590428

Reference yield:

: 2508-01-2
3-(2-chloroethyl)-2-oxazolidinone

: 59849-49-9
(-)-(R)-3-<2-<4-(8-Fluor-10,11-dihydro-2-methyldibenzo thiepin-10-yl)-1-piperazinyl>-aethyl>-2-oxazolidinon

Guidance literature:: Multi-step reaction with 3 steps

1: KI, K₂CO₃ / toluene / Heating

2: H₂ / Pd-C / methanol / 16 h / 50 °C

3: CHCl₃ / 42 h / Heating

With hydrogen; potassium carbonate; potassium iodide; palladium on activated charcoal; In methanol; chloroform; toluene;
DOI:10.1002/hlca.19760590428