8-Methoxy-4-methyl-5-nitroquinolin-2(1h)-one

Base Information

Chemical Name:8-Methoxy-4-methyl-5-nitroquinolin-2(1h)-one
CAS No.:50553-65-6
Molecular Formula:C11H10N2O4
Molecular Weight:234.2081
Hs Code.:
NSC Number:156980
DSSTox Substance ID:DTXSID10303150
Wikidata:Q82048297
Mol file:50553-65-6.mol

Synonyms:8-methoxy-4-methyl-5-nitroquinolin-2(1h)-one;50553-65-6;8-methoxy-4-methyl-5-nitro-1H-quinolin-2-one;NSC156980;DTXSID10303150;NSC-156980;A828356

Suppliers and Price of 8-Methoxy-4-methyl-5-nitroquinolin-2(1h)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 8-Methoxy-4-methyl-5-nitroquinolin-2(1h)-one

Chemical Property:

Vapor Pressure:3.43E-09mmHg at 25°C
Boiling Point:475°C at 760 mmHg
Flash Point:241.1°C
Density:1.331g/cm³
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:234.06405680
Heavy Atom Count:17
Complexity:374

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=O)NC2=C(C=CC(=C12)[N+](=O)[O-])OC

Technology Process of 8-Methoxy-4-methyl-5-nitroquinolin-2(1h)-one

There total 2 articles about 8-Methoxy-4-methyl-5-nitroquinolin-2(1h)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 30198-01-7
8-methoxy-4-methyl-1H-quinolin-2-one

: 50553-65-6
8-methoxy-4-methyl-6-nitro-2(1H)-quinolone

: 50553-66-7
8-methoxy-4-methyl-5-nitro-2(1H)-quinolone

Guidance literature:: With nitric acid; In acetic anhydride;
DOI:10.1021/jm00162a002

Reference yield:

: 50553-65-6
8-methoxy-4-methyl-6-nitro-2(1H)-quinolone

Guidance literature:: 8-Methoxy-4-methyl-2-chinolon, Acetanhydrid, HNO2;
DOI:10.1021/ja00796a037

Reference yield:

: 50553-65-6
8-methoxy-4-methyl-6-nitro-2(1H)-quinolone

: 30198-01-7
8-methoxy-4-methyl-1H-quinolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / H₂ / platinum oxide / ethanol / 3.5 h

2: 1.) conc. aq. HCl, NaNO₂ / 2.) 70 deg C, 1 h

With hydrogenchloride; hydrogen; sodium nitrite; platinum(IV) oxide; In ethanol;
DOI:10.1021/jm00162a002