Acetic acid, [[3-[2-amino-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H) -pyrimidinyl]-4-fluorophenoxy]-2-pyridinyl]oxy]-, methyl ester

Base Information

Chemical Name:Acetic acid, [[3-[2-amino-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H) -pyrimidinyl]-4-fluorophenoxy]-2-pyridinyl]oxy]-, methyl ester
CAS No.:353293-00-2
Molecular Formula:C20H16F4N4O6
Molecular Weight:484.364
Hs Code.:

Acetic acid,
[[3-[2-amino-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)
-pyrimidinyl]-4-fluorophenoxy]-2-pyridinyl]oxy]-, methyl ester

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetic acid, [[3-[2-amino-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H) -pyrimidinyl]-4-fluorophenoxy]-2-pyridinyl]oxy]-, methyl ester

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Technology Process of Acetic acid, [[3-[2-amino-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H) -pyrimidinyl]-4-fluorophenoxy]-2-pyridinyl]oxy]-, methyl ester

There total 2 articles about Acetic acid, [[3-[2-amino-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H) -pyrimidinyl]-4-fluorophenoxy]-2-pyridinyl]oxy]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 353292-99-6
3-{4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]-2-nitrophenoxy}-2-(methoxycarbonyl)methoxypyridine

: 353293-00-2
3-{2-amino-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(methoxycarbonyl)methoxypyridine

Guidance literature:: 3-{4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]-2-nitrophenoxy}-2-(methoxycarbonyl)methoxypyridine; With iron; acetic acid; In water; at 35 ℃; for 2h;

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield:

: 353292-99-6
3-{4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]-2-nitrophenoxy}-2-(methoxycarbonyl)methoxypyridine

: 7439-89-6
iron

: 353293-00-2
3-{2-amino-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(methoxycarbonyl)methoxypyridine

Guidance literature:: In water; acetic acid;

Reference yield:

: 353293-00-2
3-{2-amino-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(methoxycarbonyl)methoxypyridine

: 353292-14-5
methyl 2-((3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-(trifluoromethyl)-2,3-dihydropyrimidin-1(6H)-yl)phenoxy)pyridin-2-yl)oxy)acetate

Guidance literature:: 3-{2-amino-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-2-(methoxycarbonyl)methoxypyridine; With copper(l) chloride; copper dichloride; isopentyl nitrite; In acetonitrile; at 20 ℃; for 1h;

With hydrogenchloride; In water; acetonitrile;