Benzeneacetic acid, a-methyl-4-(1-methylethyl)-

Base Information

Chemical Name:Benzeneacetic acid, a-methyl-4-(1-methylethyl)-
CAS No.:3585-48-6
Molecular Formula:C12H16O2
Molecular Weight:192.258
Hs Code.:
Mol file:3585-48-6.mol

Synonyms:ibuprophen;2-(4-Isopropylphenyl)-propionsaeure;α-(4'-Isopropyl-phenyl)-propionsaeure;4-Propionsaeure-isopropylbenzen;2-(4-Isopropyl-phenyl)-propionic acid;2-(4-Isopropyl)-phenylpropansaeure;2-(4-isopropylphenyl)propionic acid;

Suppliers and Price of Benzeneacetic acid, a-methyl-4-(1-methylethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Isopropylphenyl)propanoicacid
100mg
$ 940.00

TRC
2-(4-Isopropylphenyl)propanoicacid
10mg
$ 125.00

Total 5 raw suppliers

Chemical Property of Benzeneacetic acid, a-methyl-4-(1-methylethyl)-

Chemical Property:

Melting Point:58 - 60 °C
PSA：37.30000
LogP:2.99810

Purity/Quality:

95% ^*data from raw suppliers

2-(4-Isopropylphenyl)propanoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-(4-Isopropylphenyl)propanoic acid is an impurity of Ibuprofen (I140010), a nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.

Technology Process of Benzeneacetic acid, a-methyl-4-(1-methylethyl)-

There total 5 articles about Benzeneacetic acid, a-methyl-4-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-Hydroxy-2-(4-isopropyl-phenyl)-propionic acid

: 3585-48-6
(R,S)-2-(4'-isopropylphenyl) propionic acid

Guidance literature:: With formic acid; palladium on activated charcoal; In hexane; for 6h; Yield given; Ambient temperature;
DOI:10.1016/S0040-4020(01)81926-8

Reference yield:

: 645-13-6
4-isopropylacetophenone

: 3585-48-6
(R,S)-2-(4'-isopropylphenyl) propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: t-BuOK / hexane / 20 °C

2: 85 percent aq. HCOOH / 10 percent Pd/C / hexane / 20 °C

With formic acid; potassium tert-butylate; palladium on activated charcoal; In hexane; 1: Addition / 2: Hydrogenolysis;

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: 59770-99-9
(+/-)-1-bromo-1-(4-isopropylphenyl)ethane

: 3585-48-6
(R,S)-2-(4'-isopropylphenyl) propionic acid

Guidance literature:: With Ag nano wire core encapsulated by a N-doped carbon shell at 700 °C; In acetonitrile; at 25 ℃; under 750.075 Torr; Reagent/catalyst; Electrochemical reaction;
DOI:10.1002/cssc.201801612