6-phenylthieno[2,3-d]pyrimidin-4(3H)-one

Base Information

Chemical Name:6-phenylthieno[2,3-d]pyrimidin-4(3H)-one
CAS No.:35970-78-6
Molecular Formula:C12H8N2OS
Molecular Weight:228.274
Hs Code.:2934999090
European Community (EC) Number:808-659-3
DSSTox Substance ID:DTXSID10350563
Nikkaji Number:J3.116.887B
Wikidata:Q82126585
ChEMBL ID:CHEMBL1400531
Mol file:35970-78-6.mol

Synonyms:6-phenylthieno[2,3-d]pyrimidin-4(3H)-one;35970-78-6;6-Phenyl-3H-thieno[2,3-d]pyrimidin-4-one;6-Phenylthieno[2,3-d]pyrimidin-4-ol;6-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one;Maybridge3_003073;Cambridge id 6942620;MLS000124081;SCHEMBL4416533;CHEMBL1400531;SCHEMBL11489324;DTXSID10350563;HMS1439L15;HMS2496H24;MFCD01564518;STL228270;AKOS000273181;AKOS015900165;CCG-240567;FS-1647;IDI1_014460;SMR000124527;CS-0451625;FT-0765399;EN300-17111;SR-01000477040;SR-01000477040-1;Z56884142

Suppliers and Price of 6-phenylthieno[2,3-d]pyrimidin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
6-Phenylthieno[2,3-d]pyrimidin-4(3H)-one
1g
$ 162.00

Crysdot
6-Phenylthieno[2,3-d]pyrimidin-4(3H)-one 95+%
5g
$ 470.00

Chemenu
6-Phenylthieno[2,3-d]pyrimidin-4(3H)-one 95%
5g
$ 445.00

American Custom Chemicals Corporation
6-PHENYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE 95.00%
1G
$ 865.90

AK Scientific
6-Phenylthieno[2,3-d]pyrimidin-4(3H)-one
500mg
$ 372.00

Total 7 raw suppliers

Chemical Property of 6-phenylthieno[2,3-d]pyrimidin-4(3H)-one

Chemical Property:

Melting Point:220°C
PSA：74.25000
LogP:3.06390
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:228.03573406
Heavy Atom Count:16
Complexity:312

Purity/Quality:

99% ^*data from raw suppliers

6-Phenylthieno[2,3-d]pyrimidin-4(3H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC3=C(S2)N=CNC3=O

Technology Process of 6-phenylthieno[2,3-d]pyrimidin-4(3H)-one

There total 8 articles about 6-phenylthieno[2,3-d]pyrimidin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 4815-34-3
ethyl 2-amino-5-phenylthiophene-3-carboxylate

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 35970-78-6
6-phenylthieno[2,3-d]pyrimidin-4(3H)-one

Guidance literature:: at 190 ℃; for 2.5h;

Reference yield: 87.0%

: 98-80-6
phenylboronic acid

: 56844-40-7
6-bromothieno[2,3-d]pyrimidin-4(3H)-one

: 35970-78-6
6-phenylthieno[2,3-d]pyrimidin-4(3H)-one

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; at 110 ℃; for 5h;
DOI:10.1016/j.tet.2012.08.090

Reference yield:

: 122-78-1
phenylacetaldehyde

: 35970-78-6
6-phenylthieno[2,3-d]pyrimidin-4(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: sulfur; triethylamine / diethyl ether / 12 h / 20 °C

2: 24 h / 160 - 170 °C

With sulfur; triethylamine; In diethyl ether;
DOI:10.1016/j.ejmech.2010.12.025