4815-34-3Relevant articles and documents
Microwave-assisted synthesis of 2-aminothiophene derivatives via improved gewald reactions
Ruan, Bankang,Zhang, Zhiyan,Huang, Lei,Xu, Chao,Li, Luolan
, p. 2007 - 2018 (2021/09/29)
In this paper, a new and efficient method was developed to prepare 2-aminothiophene derivatives through improved Gewald reaction. Thirty-one final products were synthesized under microwave radiation for 30 min with 57%-95% isolated yields. All the product
The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori That Act through Inhibition of the Respiratory Complex i
Mugengana, Alex K.,Vita, Nicole A.,Brown Gandt, Autumn,Moran, Kevin,Agyapong, George,Sharma, Lalit K.,Griffith, Elizabeth C.,Liu, Jiuyu,Yang, Lei,Gavrish, Ekaterina,Hevener, Kirk E.,Lafleur, Michael D.,Lee, Richard E.
, p. 1044 - 1058 (2021/02/09)
The successful treatment of Helicobacter pylori infections is becoming increasingly difficult due to the rise of resistance against current broad spectrum triple therapy regimens. In the search for narrow-spectrum agents against H. pylori, a high-throughp
ACLY INHIBITORS AND USES THEREOF
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Paragraph 00767, (2020/06/01)
The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.