6-HYDROXY-2-PROPYL-4(3H)-PYRIMIDINONE

Base Information

• Chemical Name: 6-HYDROXY-2-PROPYL-4(3H)-PYRIMIDINONE
• CAS No.: 3603-18-7
• Molecular Formula: C7H10N2O2
• Molecular Weight: 154.169
• Mol file: 3603-18-7.mol

Synonyms:6-hydroxy-2-(n-propyl)-[3H]-pyrimidin-4-one;6-Hydroxy-2-propyl-3H-pyrimidin-4-one;6-HYDROXY-2-PROPYL-4(3H)-PYRIMIDINONE;2-PROPYLPYRIMIDINE-4,6-DIOL;

Chemical Property of 6-HYDROXY-2-PROPYL-4(3H)-PYRIMIDINONE

Chemical Property:

• PSA: 66.24000
• LogP: 0.84030

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-HYDROXY-2-PROPYL-4(3H)-PYRIMIDINONE

There total 3 articles about 6-HYDROXY-2-PROPYL-4(3H)-PYRIMIDINONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

butylamidine hydrochloride (3020-81-3) + diethyl malonate (105-53-3) → 2-propyl-1H-pyrimidine-4,6-dione (3603-18-7)

Guidance literature:

With sodium ethanolate; In ethanol; for 4h; Reflux; Green chemistry;

DOI:10.1071/CH14073

Reference yield:

→ 2-propyl-1H-pyrimidine-4,6-dione (3603-18-7)

Guidance literature:

Prep.: gemaess Vorschrift Henze, McPherson, J. Org. Chem. 18 (1953) 653;

Reference yield:

→ 6-hydroxy-2-(n-propyl)-[3H]-pyrimidin-4-one (3603-18-7)

Guidance literature:

Diethylmalonat, Butanamidiniumchlorid;

upstream raw materials:

butylamidine hydrochloride

diethyl malonate

Downstream raw materials:

2-n-propyl-4,6-dichloropyrimidine