5,7-DIBROMO INDOLE

Base Information

• Chemical Name: 5,7-DIBROMO INDOLE
• CAS No.: 36132-08-8
• Molecular Formula: C8H5Br2N
• Molecular Weight: 274.942
• Hs Code.: 2933990090
• Mol file: 36132-08-8.mol

Synonyms:1H-Indole,5,7-dibromo;5,7-Dibromo-1H-indole;5,7-DIBROMO INDOLE;5,7-Dibromindol;

Chemical Property of 5,7-DIBROMO INDOLE

Chemical Property:

• Vapor Pressure: 2.68E-05mmHg at 25°C
• Melting Point: 67-72°C
• Boiling Point: 368.5oC at 760 mmHg
• Flash Point: 176.7oC
• PSA: 15.79000
• Density: 2.048g/cm3
• LogP: 3.69290
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

5,7-Dibromoindole 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-37/38-41
• Safety Statements: 26-39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 5,7-DIBROMO INDOLE

There total 1 articles about 5,7-DIBROMO INDOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.9%

sodium 1-acetyl-1H-indole-2-sulfonate → 5-bromo-1H-indole (10075-50-0) + 5,7-dibromo-1H-indole (36132-08-8)

Guidance literature:

sodium 1-acetyl-1H-indole-2-sulfonate; With bromine; In water; at 0 - 20 ℃; for 2h;

With sodium hydrogensulfite; sodium hydroxide; In water; for 20h; Reflux;

DOI:10.1016/j.tetlet.2015.05.024

Reference yield: 94.0%

5,7-dibromo-1H-indole (36132-08-8) + benzyl bromide (100-39-0) → 1-benzyl-5,7-dibromo-1H-indole

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; for 24h; Green chemistry;

DOI:10.1039/d1ob02058g

Reference yield: 85.0%

5,7-dibromo-1H-indole (36132-08-8) + 2-Methoxyphenylboronic acid (5720-06-9) → 5,7-bis(2-methoxyphenyl)-1H-indole

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; at 120 ℃; for 1h; Inert atmosphere; Microwave irradiation; Sealed tube; Green chemistry;

DOI:10.1039/d1ob02058g

Downstream raw materials:

C₁₅H₁₂BrNO

C₂₂H₁₉NO₂

5-bromo-7-(4-methoxyphenyl)-1H-indole

5,7-dibromo-1H-indole-3-carbaldehyde

Refernces