1-methyl-2-phenyl-1H-indene

Base Information

• Chemical Name: 1-methyl-2-phenyl-1H-indene
• CAS No.: 3661-63-0
• Molecular Formula: C16H14
• Molecular Weight: 206.287
• DSSTox Substance ID: DTXSID80372959
• Nikkaji Number: J1.396.910H
• Mol file: 3661-63-0.mol

Synonyms:1-methyl-2-phenylindene;1-methyl-2-phenyl-1H-indene;3661-63-0;DTXSID80372959;SOKYZLBJLDLMTR-UHFFFAOYSA-N;AKOS004907862

Chemical Property of 1-methyl-2-phenyl-1H-indene

Chemical Property:

• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 206.109550447
• Heavy Atom Count: 16
• Complexity: 270

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1C2=CC=CC=C2C=C1C3=CC=CC=C3

Technology Process of 1-methyl-2-phenyl-1H-indene

There total 29 articles about 1-methyl-2-phenyl-1H-indene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-bromo-1-methyl-1H-indene (78176-77-9) + phenylboronic acid (98-80-6) → 1-methyl-2-phenyl-1H-indene (3661-63-0)

Guidance literature:

With barium hydroxide octahydrate; palladium diacetate; tris-(o-tolyl)phosphine; In 1,2-dimethoxyethane; water; at 50 ℃; for 1.5h; Inert atmosphere;

DOI:10.1021/ol203209b

Reference yield: 88.0%

2-(2-(2-methylprop-1-en-1-yl)phenyl)-1-phenylpropan-1-one → 1-methyl-2-phenyl-1H-indene (3661-63-0)

Guidance literature:

With toluene-4-sulfonic acid; at 20 ℃; for 4h; Reagent/catalyst; Catalytic behavior; Sealed tube;

DOI:10.1002/anie.202117366

Reference yield: 80.0%

2-Phenyl-3-methylindanol (65451-65-2) → 1-methyl-2-phenyl-1H-indene (3661-63-0)

Guidance literature:

With sulfuric acid; In acetic acid; at 25 ℃; for 2h;

DOI:10.1021/jo00322a023

upstream raw materials:

2-Phenyl-3-methylindanone

2-Phenyl-3-methylindanol

1,1-diphenyl-1,2-epoxy-2-methylpropane

2,3-dimethyl-2,3-diphenylethylene oxide

Downstream raw materials:

1-allyl-2-phenyl-3-methylindene

(1R,8S,9R)-8-Methyl-9-phenyl-10,11,12-trioxa-tricyclo[7.2.1.0^2,7]dodeca-2⁽⁷⁾,3,5-triene

(1R,8R,9R)-8-Methyl-9-phenyl-10,11,12-trioxa-tricyclo[7.2.1.0^2,7]dodeca-2⁽⁷⁾,3,5-triene

(pentamethylcyclopentadienyl)(1-methyl-2-phenylindenyl)zirconium dichloride

Refernces

• 1、 Rimkus, Andrea M.,Alt, Helmut G.. "Dissymmetric ansa zirconocene complexes with di- and trisubstituted indenyl ligands as catalysts for homogeneous ethylene homo- and ethylene/1-hexene copolymerization reactions". . p. 72 - 82. Retrieved 2017/02/18.
• 2、 Usanov, Dmitry L.,Naodovic, Marina,Brasholz, Malte,Yamamoto, Hisashi. "Gold(I)-catalyzed cyclodehydration enabled by the triisopropylsilyl group: A synthetically versatile methodology". . p. 1773 - 1789,17. Retrieved 2012/12/12.