2,2-Dimethyl-3,3-diphenyloxirane

Base Information

• Chemical Name: 2,2-Dimethyl-3,3-diphenyloxirane
• CAS No.: 60227-39-6
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• DSSTox Substance ID: DTXSID40383506
• Nikkaji Number: J1.694.449A
• Wikidata: Q82175257
• Mol file: 60227-39-6.mol

Synonyms:2,2-dimethyl-3,3-diphenyloxirane;60227-39-6;Oxirane, 2,2-dimethyl-3,3-diphenyl-;SCHEMBL19809331;DTXSID40383506;2,2-dimethyl-3,3-diphenyl-oxirane;MFCD00205667;AKOS015905961;1,1-Diphenyl-1,2-epoxy-2-methylpropane

Chemical Property of 2,2-Dimethyl-3,3-diphenyloxirane

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 224.120115130
• Heavy Atom Count: 17
• Complexity: 251

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1(C(O1)(C2=CC=CC=C2)C3=CC=CC=C3)C

Technology Process of 2,2-Dimethyl-3,3-diphenyloxirane

There total 13 articles about 2,2-Dimethyl-3,3-diphenyloxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-methyl-1,1-diphenylpropene (781-33-9) → 1,1-diphenyl-1,2-epoxy-2-methylpropane (60227-39-6) + benzoic acid phenyl ester (93-99-2) + biphenyl (92-52-4,1594-86-1)

Guidance literature:

With oxygen; benzil; In benzene; at 5 ℃; for 0.25h; Irradiation;

DOI:10.1021/ja00375a031

Reference yield: 80.0%

2-methyl-1,1-diphenylpropene (781-33-9) → 1,1-diphenyl-1,2-epoxy-2-methylpropane (60227-39-6)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.1002/ejoc.201201191

Reference yield: 8.0%

2-methyl-1,1-diphenylpropene (781-33-9) → benzophenone (119-61-9) + 1,1-diphenyl-1,2-epoxy-2-methylpropane (60227-39-6)

Guidance literature:

With chromyl nitrate; In tetrachloromethane; dichloromethane; N,N-dimethyl-formamide; at -78 ℃;

DOI:10.1021/ja00346a044

upstream raw materials:

2-methyl-1,1-diphenylpropene

2-methyl-1,1-diphenyl-propan-2-ol

phenylmagnesium bromide

phenyl isopropyl ketone

Downstream raw materials:

3,3-diphenylbutan-2-one

1-methyl-2-phenyl-1H-indene

2-methyl-1,2-diphenyl-propan-1-one

2-methyl-1,1-diphenylpropene

Refernces

• 1、 Skliri, Euaggelia,Lykakis, Ioannis N.,Armatas, Gerasimos S.. "Heteropolytungstic acids incorporated in an ordered mesoporous zirconia framework as efficient oxidation catalysts". . p. 8402 - 8409. Retrieved 2014/02/14.
• 2、 Hayashi, Yujiro,Takeda, Mitsuhiro,Miyamoto, Yuji,Shoji, Mitsuru. "Oxidative double bond cleavage of α-substituted styrenes with molecular oxygen". . p. 414 - 415. Retrieved 2007/10/03.