1,2-Bis(3-methoxyphenyl)ethane

Base Information

• Chemical Name: 1,2-Bis(3-methoxyphenyl)ethane
• CAS No.: 36707-27-4
• Molecular Formula: C16H18O2
• Molecular Weight: 242.318
• European Community (EC) Number: 667-858-1
• Nikkaji Number: J462.269C
• Mol file: 36707-27-4.mol

Synonyms:1,2-bis(3-methoxyphenyl)ethane;36707-27-4;3,3'-ETHYLENEBIS(ANISOLE);SCHEMBL723511;BTARCYDJTMRPBY-UHFFFAOYSA-N;1,2-bis (m-methoxylphenyl)ethane;MFCD00091046;AKOS024338083

Chemical Property of 1,2-Bis(3-methoxyphenyl)ethane

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 242.130679813
• Heavy Atom Count: 18
• Complexity: 205

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)CCC2=CC(=CC=C2)OC

Technology Process of 1,2-Bis(3-methoxyphenyl)ethane

There total 82 articles about 1,2-Bis(3-methoxyphenyl)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-bromomethyl-3-methoxybenzene (874-98-6) → 1,2-bis(3-methoxyphenyl)ethane (36707-27-4)

Guidance literature:

With potassium phosphate; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; In N,N-dimethyl-formamide; at 20 ℃; for 4h; Inert atmosphere; Irradiation;

DOI:10.1002/chem.201603517

Reference yield: 69.0%

m-methoxybenzyl chloride (824-98-6) → 1,2-bis(3-methoxyphenyl)ethane (36707-27-4) + 1-methoxy-3-methyl-benzene (100-84-5)

Guidance literature:

With nickel; In 1,2-dimethoxyethane; for 6h; Ambient temperature;

DOI:10.1021/jo00186a003

Reference yield: 68.0%

(3-methoxybenzyl)trimethylsilane (51755-56-7) → 3-methoxybenzyl alcohol (6971-51-3) + 1,2-bis(3-methoxyphenyl)ethane (36707-27-4)

Guidance literature:

With titanium(IV) oxide; silver sulfate; In water; acetonitrile; for 0.5h; Irradiation;

upstream raw materials:

ethanol

bis(3-methoxyphenyl)acetylene

m-methoxyphenylacetic acid

m-methoxybenzyl chloride

Downstream raw materials:

3,3'-(ethane-1,2-diyl)diphenol

1,2-bis(2-iodo-5-methoxyphenyl)ethane

2,7-dimethoxyphenanthrene