7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane

Base Information

Chemical Name:7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS No.:36793-27-8
Molecular Formula:C11H21NO2
Molecular Weight:199.293
Hs Code.:
European Community (EC) Number:609-294-0
UNII:4O0H80TW9F
DSSTox Substance ID:DTXSID901043464
Wikidata:Q27260259
Mol file:36793-27-8.mol

Synonyms:36793-27-8;Triacetoneamine ethylene ketal;7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane;Triacetonamine ethylene glycol ketal;2,2,6,6-tetramethyl-4-piperidone ethylene ketal;UNII-4O0H80TW9F;1,4-Dioxa-8-aza-7,7,9,9-tetramethylspiro(4.5)decane;4O0H80TW9F;1,4-Dioxa-8-azaspiro[4.5]decane, 7,7,9,9-tetramethyl-;Triacetoneamine ethylene glycol ketal;2,2,6,6-Tetramethyl-4-oxo-1-piperidine ethylene ketal;7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro(4.5)decane;8-Aza-7,7,9,9-tetramethyl-1,4-dioxaspiro(4.5)decane;1,4-Dioxa-8-azaspiro(4.5)decane, 7,7,9,9-tetraemtheyl-;1,4-Dioxa-8-aza-7,7,9,9-tetramethylspiro[4.5]decane;1,4-DIOXA-8-AZASPIRO[4.5]DECANE, 7,7,9,9-TETRAEMTHEYL-;LS-181659;4,4-ethylenedioxy-2,2,6,6-tetramethylpiperidine;SCHEMBL1831266;DTXSID901043464;Q27260259;7,7,9,9-tetramethyl-8-aza-1,4-dioxaspiro[4.5]decane;1,4-Dioxa-8-azaspiro[4.5]decane, 7,7,9,9-tetramethyl

Suppliers and Price of 7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane

Chemical Property:

Vapor Pressure:0.0159mmHg at 25°C
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:199.157228913
Heavy Atom Count:14
Complexity:211

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC2(CC(N1)(C)C)OCCO2)C

Technology Process of 7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane

There total 2 articles about 7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 826-36-8
2,2,6,6-Tetramethyl-4-piperidone

: 107-21-1
ethylene glycol

: 36793-27-8
7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane

Guidance literature:: 2,2,6,6-Tetramethyl-4-piperidone; ethylene glycol; With hydrogenchloride; In toluene; at 80 ℃; Heating / reflux;

With sodium hydroxide; In water; toluene; pH=11;

Reference yield:

: 36793-27-8
7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane

Guidance literature:: 2,2,6,6-Tetramethyl-piperidon-(4)-hydrochlorid, Aethandiol-(1,2), p-Toluolsulfonsaeure, Bzl.;
DOI:10.1007/BF00905909

Reference yield: 68.0%

: 216439-76-8
(S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate

: 36793-27-8
7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane

: (S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-((7,9,9-trimethyl-1,4-dioxa-8-azaspiro[4.5]decan-7-yl)methyl)phenyl)propanoate

Guidance literature:: With (S)-2-acetylamino-3-phenylpropanoic acid; palladium diacetate; sodium hydrogencarbonate; silver carbonate; p-benzoquinone; In tert-Amyl alcohol; at 80 ℃; for 16h; Sealed tube;
DOI:10.1002/anie.201508912