2-(acetyloxy)-1,2-diphenylethyl acetate

Base Information

• Chemical Name: 2-(acetyloxy)-1,2-diphenylethyl acetate
• CAS No.: 3682-07-3
• Molecular Formula: C18H18O4
• Molecular Weight: 298.339
• Hs Code.: 2915390090
• Mol file: 3682-07-3.mol

Synonyms:1,2-diphenyl-1,2-di(4-methoxyphenyl)-ethane-1,2-diol;1,2-Diphenyl-1,2-diacetoxyethane;1,2-bis(4-methoxyphenyl)-1,2-diphenyl-1,2-ethanediol;1,2-Bis-(4-methoxy-phenyl)-1,2-diphenyl-aethan-1,2-diol;meso-Hydrobenzoindiacetat;1,2-diacetoxy-1,2-diphenylethane;1,2-Ethanediol,1,2-bis(4-methoxyphenyl)-1,2-diphenyl;1,2-diphenyl-1,2-di(4-methoxyphenyl)-1,2-ethanediol;dl-Hydrobenzoindiacetat;1.2-Dihydroxy-1.2-diphenyl-1.2-bis-(4-methoxy-phenyl)-aethan;1,2-diphenyl-1,2-ethanediyl diacetate;dihydrobenzoin diacetate;1,2-bis-(4-methoxy-phenyl)-1,2-diphenyl-ethane-1,2-diol;

Chemical Property of 2-(acetyloxy)-1,2-diphenylethyl acetate

Chemical Property:

• Vapor Pressure: 1.24E-06mmHg at 25°C
• Boiling Point: 400.8oC at 760 mmHg
• Flash Point: 195.9oC
• PSA: 52.60000
• Density: 1.158g/cm3
• LogP: 3.59520

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(acetyloxy)-1,2-diphenylethyl acetate

There total 70 articles about 2-(acetyloxy)-1,2-diphenylethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

cis-stilben (645-49-8) + acetic acid (64-19-7,77671-22-8) → anti-acetic acid 2-acetoxy-1,2-diphenyl-ethyl ester (3682-07-3,6316-82-1,63435-67-6,66749-68-6,67650-45-7,113216-89-0)

Guidance literature:

With oxygen; palladium diacetate; potassium iodide; at 100 ℃; for 24h; under 6080.41 Torr; optical yield given as %de; diastereoselective reaction; Autoclave;

Reference yield: 77.0%

(E)-1,2-diphenyl-ethene (103-30-0) + acetic acid (64-19-7,77671-22-8) → syn-acetic acid 2-acetoxy-1,2-diphenyl-ethyl ester (3682-07-3,6316-82-1,63435-67-6,66749-68-6,67650-45-7,113216-89-0)

Guidance literature:

With oxygen; palladium diacetate; potassium iodide; at 100 ℃; for 24h; under 6080.41 Torr; optical yield given as %de; diastereoselective reaction; Autoclave;

Reference yield: 77.0%

(E)-1,2-diphenyl-ethene (103-30-0) + acetic anhydride (108-24-7) → anti-acetic acid 2-acetoxy-1,2-diphenyl-ethyl ester (3682-07-3,6316-82-1,63435-67-6,66749-68-6,67650-45-7,113216-89-0) + syn-acetic acid 2-acetoxy-1,2-diphenyl-ethyl ester (3682-07-3,6316-82-1,63435-67-6,66749-68-6,67650-45-7,113216-89-0)

Guidance literature:

With 2,2':6,2''-terpyridine; oxygen; palladium diacetate; acetic acid; bis(pinacol)diborane; In acetonitrile; at 90 ℃; for 24h; under 760.051 Torr; diastereoselective reaction; Sealed tube;

DOI:10.1021/acs.orglett.8b01806

upstream raw materials:

1,2-diphenyl-1,2-ethanediol

acetic anhydride

DL-1,2-diphenylethane-1,2-diol

acetic acid

Downstream raw materials:

(R,R)-hydroxybenzoin

Phosphoric acid mono-[2-hydroxy-1,2-bis-(4-nitro-phenyl)-ethyl] ester; compound with cyclohexylamine

Ammonium 4,4'-dinitrohydrobenzoin-cyclophosphat

Methyl 4,4'-dinitrohydrobenzoin phosphate

Refernces

• 1、 Huang, Jiuzhong,Ouyang, Lu,Li, Jianxiao,Zheng, Jia,Yan, Wuxin,Wu, Wanqing,Jiang, Huanfeng. "B2pin2-Mediated Palladium-Catalyzed Diacetoxylation of Aryl Alkenes with O2 as Oxygen Source and Sole Oxidant". supporting information. p. 5090 - 5093. Retrieved 2018/09/12.
• 2、 Zhong, Wenhe,Liu, Shan,Yang, Jun,Meng, Xiangbao,Li, Zhongjun. "Metal-free, organocatalytic syn diacetoxylation of alkenes". supporting information; experimental part. p. 3336 - 3339. Retrieved 2012/08/29.