2-(p-Tolyl)-2H-indazole

Base Information

Chemical Name:2-(p-Tolyl)-2H-indazole
CAS No.:3682-73-3
Molecular Formula:C14H12N2
Molecular Weight:208.263
Hs Code.:
DSSTox Substance ID:DTXSID60454282
Nikkaji Number:J683.634H
Wikidata:Q82275714
Mol file:3682-73-3.mol

Synonyms:2-(p-Tolyl)-2H-indazole;3682-73-3;2-P-TOLYL-2H-INDAZOLE;2h-indazole,2-(4-methylphenyl)-;2-(4-Methylphenyl)-2H-indazole;2H-Indazole, 2-(4-methylphenyl)-;SCHEMBL14005778;DTXSID60454282;MFCD20921677

Suppliers and Price of 2-(p-Tolyl)-2H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(p-Tolyl)-2H-indazole

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:208.100048391
Heavy Atom Count:16
Complexity:233

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2C=C3C=CC=CC3=N2

Technology Process of 2-(p-Tolyl)-2H-indazole

There total 34 articles about 2-(p-Tolyl)-2H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1-acetyl-2-(4-methylphenyl)dihydroindazole

: 3682-73-3
2-(4-methylphenyl)-2H-indazole

Guidance literature:: 1-acetyl-2-(4-methylphenyl)dihydroindazole; With sodium hydroxide; In methanol; at 70 ℃; for 0.5h;

With oxygen; In dichloromethane; Further stages.;

Reference yield: 94.0%

: 3483-19-0
3-(4-methylphenyl)sydnone

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 3682-73-3
2-(4-methylphenyl)-2H-indazole

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 12h; Sealed flask;
DOI:10.1021/ol100586r

Reference yield: 93.0%

: 106-49-0,12221-03-3
p-toluidine

: 6630-33-7
ortho-bromobenzaldehyde

: 3682-73-3
2-(4-methylphenyl)-2H-indazole

Guidance literature:: p-toluidine; ortho-bromobenzaldehyde; With sodium azide; In dimethyl sulfoxide; at 20 ℃; for 0.0833333h; Inert atmosphere;

With 1,10-Phenanthroline; copper(I) oxide; In dimethyl sulfoxide; at 80 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1002/cmdc.201800707