2-Furancarboximidamide, N-phenyl-

Base Information

• Chemical Name: 2-Furancarboximidamide, N-phenyl-
• CAS No.: 3688-57-1
• Molecular Formula: C11H10N2O
• Molecular Weight: 186.213
• DSSTox Substance ID: DTXSID80444665
• Nikkaji Number: J655.508J
• Mol file: 3688-57-1.mol

Synonyms:2-Furancarboximidamide, N-phenyl-;3688-57-1;DTXSID80444665

Chemical Property of 2-Furancarboximidamide, N-phenyl-

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 186.079312947
• Heavy Atom Count: 14
• Complexity: 209

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N=C(C2=CC=CO2)N

Technology Process of 2-Furancarboximidamide, N-phenyl-

There total 6 articles about 2-Furancarboximidamide, N-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2-furancarbonitrile (617-90-3) + aniline (62-53-3) → N2-Phenylfuran-2-carboximidamide (3688-57-1)

Guidance literature:

With aluminium trichloride; In dichloromethane;

DOI:10.1039/b010010m

Reference yield: 23.0%

furan-5-carboxamidine (54610-73-0) + 1,2-Diiodobenzene (615-42-9) → fuberidazole (3878-19-1) + N2-Phenylfuran-2-carboximidamide (3688-57-1)

Guidance literature:

With copper(l) iodide; caesium carbonate; N,N`-dimethylethylenediamine; In 1-methyl-pyrrolidin-2-one; at 170 ℃; Inert atmosphere;

DOI:10.1021/jo900912h

Reference yield:

furan-2-carboxylic acid amide (609-38-1) + aniline (62-53-3) → N-phenylfuran-2-carboximidamide (3688-57-1)

Guidance literature:

With trimethylaluminum; In toluene; at 0 - 110 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.8b03383

upstream raw materials:

furfural phenylhydrazone

2-furancarbonitrile

aniline

furan-2-carboxylic acid amide

Downstream raw materials:

4-chlorobenzanilide

N-phenyl benzoyl amide

N-benzoylfuran-2-carboxamide

fuberidazole