Benzenesulfonyl fluoride, 4-methoxy-

Base Information

• Chemical Name: Benzenesulfonyl fluoride, 4-methoxy-
• CAS No.: 368-91-2
• Molecular Formula: C7H7FO3S
• Molecular Weight: 190.195
• Mol file: 368-91-2.mol

Synonyms:

Chemical Property of Benzenesulfonyl fluoride, 4-methoxy-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenesulfonyl fluoride, 4-methoxy-

There total 20 articles about Benzenesulfonyl fluoride, 4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-methoxy-phenyl-sulphonyl chloride (98-68-0) → 4-methoxybenzene-1-sulfonyl fluoride (368-91-2)

Guidance literature:

With potassium hydrogen difluoride; In water; acetonitrile; at 20 ℃; for 21h;

DOI:10.1055/s-0037-1610877

Reference yield: 95.0%

4-methoxybenzene sulfonamide (1129-26-6) → 4-methoxybenzene-1-sulfonyl fluoride (368-91-2)

Guidance literature:

With potassium fluoride; pyrylium tetrafluoroborate; magnesium chloride; In acetonitrile; at 60 ℃; for 2h;

DOI:10.1002/ejoc.202000022

Reference yield: 85.0%

(E)-1-(4-methoxyphenyl)-2-(methylsulfonyl)diazene → 4-methoxybenzene-1-sulfonyl fluoride (368-91-2)

Guidance literature:

With potassium pyrosulfite; N-fluorobis(benzenesulfon)imide; In water; acetonitrile; at 20 ℃; for 4h; Reagent/catalyst; Solvent; Wavelength; Mechanism; Irradiation; Green chemistry;

DOI:10.1002/adsc.202100951

upstream raw materials:

4-methoxy-phenyl-sulphonyl chloride

1-methoxy-4-phenoxy-benzene

fluorosulphonic acid

methoxybenzene

Downstream raw materials:

4-methoxybenzene sulfonamide

2,2,2-trifluoro-N-{1-[4-(4-methoxy-benzenesulfonyl)-phenyl]-ethyl}-acetamide

4-[4-(4-methoxy-benzenesulfonyl)-benzyl]-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester

2,2,2-trifluoro-N-(1-{4-[4-methoxy-2-(4-methoxy-benzenesulfonyl)-benzenesulfonyl]-phenyl}-ethyl)-acetamide

Refernces

• 1、 Bui, Tien Tan,Tran, Van Hieu,Kim, Hee-Kwon. "Visible-Light-Mediated Synthesis of Sulfonyl Fluorides from Arylazo Sulfones". . p. 341 - 347. Retrieved 2021/10/14.
• 2、 Cornella, Josep,Magre, Marc. "Redox-Neutral Organometallic Elementary Steps at Bismuth: Catalytic Synthesis of Aryl Sulfonyl Fluorides". supporting information. p. 21497 - 21502. Retrieved 2022/01/03.