1-Propanone, 1-(4-hydroxyphenyl)-3-phenyl-

Base Information

• Chemical Name: 1-Propanone, 1-(4-hydroxyphenyl)-3-phenyl-
• CAS No.: 36941-00-1
• Molecular Formula: C15H14O2
• Molecular Weight: 226.275
• Mol file: 36941-00-1.mol

Synonyms:4'-hydroxydihydrochalcone;1-(4-hydroxy-phenyl)-3-phenyl-propan-1-one;4'-hydroxy-3-phenylpropiophenone;1-(4-hydroxyphenyl)-3-phenylpropan-1-one;1-(4-Hydroxy-phenyl)-3-phenyl-propan-1-on;

Chemical Property of 1-Propanone, 1-(4-hydroxyphenyl)-3-phenyl-

Chemical Property:

• PSA: 37.30000
• LogP: 3.20770

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Propanone, 1-(4-hydroxyphenyl)-3-phenyl-

There total 17 articles about 1-Propanone, 1-(4-hydroxyphenyl)-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4'-hydroxychalcone (2657-25-2,38239-52-0,102692-58-0) → 1-(4-hydroxyphenyl)-3-phenylpropan-1-one (36941-00-1)

Guidance literature:

With hydrogen; In ethanol; water; at 25 ℃; for 12h; under 760.051 Torr; chemoselective reaction;

DOI:10.1039/c3ra42150c

Reference yield: 87.0%

(E)-1-(4-hydroxyphenyl)-3-phenylprop-2-en-1-one (2657-25-2) → 1-(4-hydroxyphenyl)-3-phenylpropan-1-one (36941-00-1)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; silica gel; In benzene; at 70 ℃; for 18h;

DOI:10.1246/bcsj.60.4019

Reference yield: 82.0%

phenyl 3-phenylpropanoate (726-26-1) → 2'-hydroxy-3-phenylpropiophenone (3516-95-8) + 1-(4-hydroxyphenyl)-3-phenylpropan-1-one (36941-00-1)

Guidance literature:

With methanesulfonic acid; Methanesulfonic anhydride; at 65 ℃; regioselective reaction; Inert atmosphere;

DOI:10.1055/s-0032-1316568

upstream raw materials:

phenyl 3-phenylpropanoate

3-Phenylpropionic acid

phenol

(E)-1-(4-hydroxyphenyl)-3-phenylprop-2-en-1-one

Downstream raw materials:

1-[4-(3-dimethylamino-propoxy)-phenyl]-3-phenyl-propan-1-one

1-[4-(2-diethylamino-ethoxy)-phenyl]-3-phenyl-propan-1-one

1-(4-methoxyphenyl)-3-phenylpropan-1-one

6-(3-phenylpropionyl)-1,3-benzodioxane