2-(hept-6-ynyloxy)tetrahydro-2H-pyran

Base Information

• Chemical Name: 2-(hept-6-ynyloxy)tetrahydro-2H-pyran
• CAS No.: 37011-86-2
• Molecular Formula: C12H20O2
• Molecular Weight: 196.29
• Mol file: 37011-86-2.mol

Synonyms:7-[2-Tertahydropyranyloxy]-1-heptyne;2-(hept-6-ynyloxy)tetrahydropyran;tetrahydro-2-(6-heptynyloxy)-2H-pyran;6-Heptynyl tetrahydro-2H-pyran-2-yl ether;2-(hept-6-ynyloxy)tetrahydro-2H-pyran;7-(tetrahydropyran-2-yloxy)-1-heptyne;2-(hept-6-yn-1-yloxy)tetrahydro-2H-pyran;1-(2-tetrahydropyranyloxy)-6-heptyne;2H-Pyran,2-(6-heptynyloxy)tetrahydro;6-heptyn-1-ol tetrahydropyranyl ether;

Chemical Property of 2-(hept-6-ynyloxy)tetrahydro-2H-pyran

Chemical Property:

• PSA: 18.46000
• LogP: 2.72320

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(hept-6-ynyloxy)tetrahydro-2H-pyran

There total 33 articles about 2-(hept-6-ynyloxy)tetrahydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-dihydro-2H-pyran (110-87-2) + 1-hydroxy-6-heptyne (63478-76-2) → tetrahydro-2-(6-heptynyloxy)-2H-pyran (37011-86-2)

Guidance literature:

With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃;

Reference yield: 100.0%

2-(5-bromopentyloxy)tetrahydropyran (37935-47-0) + acetylene (74-86-2,25067-58-7) → tetrahydro-2-(6-heptynyloxy)-2H-pyran (37011-86-2)

Guidance literature:

acetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -10 ℃; for 0.5h;

2-(5-bromopentyloxy)tetrahydropyran; In tetrahydrofuran; hexane; dimethyl sulfoxide; at 20 ℃;

DOI:10.1002/1099-0690(200109)2001:18<3491::aid-ejoc3491>3.0.co;2-3

Reference yield: 96.0%

2-[(5-chloropentyl)oxy]tetrahydropyran (13129-60-7) + lithium acetylide-ethylenediamine complex (1216963-74-4) → tetrahydro-2-(6-heptynyloxy)-2H-pyran (37011-86-2)

Guidance literature:

In dimethyl sulfoxide; at 20 ℃; for 3h;

DOI:10.1002/jccs.199900011

upstream raw materials:

3,4-dihydro-2H-pyran

1-hydroxy-6-heptyne

hept-6-ynenitrile

2-(5-bromopentyloxy)tetrahydropyran

Downstream raw materials:

1-hydroxy-6-heptyne

(E)-6-tetradecenyl acetate

1-(tert-butyldiphenylsilyloxy)-20-(tetrahydropyran-2-yloxy)-eicosa-5,14-diyne

(E)-6-nonen-1-ol