1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

Base Information

Chemical Name:1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
CAS No.:62780-89-6
Molecular Formula:C10H11ClN2O
Molecular Weight:210.663
Hs Code.:29339980
European Community (EC) Number:263-731-6
DSSTox Substance ID:DTXSID90211845
Nikkaji Number:J307.132D

Synonyms:62780-89-6;1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one;1-(3-Chloropropyl)-1H-benzo[d]imidazol-2(3H)-one;3-(3-chloropropyl)-1H-benzimidazol-2-one;1-(3-Chloropropyl)-2-benzimidazolidinone;EINECS 263-731-6;1-(3-chloropropyl)-1,3-dihydrobenzimidazol-2-one;3-(3-chloropropyl)-2,3-dihydro-1h-benzimidazole-2-one;1-(3-chloropropyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one;1-(3-Chloropropyl)-1,3-Dihydro-2H-Benzimidazole-2-One;Domperidone Impurity 1;ChemDiv2_000053;SCHEMBL318787;SCHEMBL8185591;DTXSID90211845;GUMPYDGUYXOYML-UHFFFAOYSA-N;HMS1369C09;N-(3-chloropropyl)-benzimidazolone;AMY40874;BCP34402;BBL011730;MFCD00044896;STK802544;AKOS000121336;AC-3215;BS-9881;CS-T-12476;BB 0242378;CS-0237003;EU-0066726;FT-0640851;EN300-17637;F87303;1-(3-Chloropropyl)-1H-benzoimidazole-2(3H)-one;A868364;1(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one;1-(3-chloro propyl)-2,3-dihydro-1H-benzimidazol-2-one;1-(3-Chloro-propyl)-1,3-dihydro-benzoimidaz ol-2-one;1-(3-chloropropyl)-1,3-dihydro-2-oxo-2H-benzimidazole;1-(3-chloropropyl)-1,3-dihydro-2H-bezimidazol-2-one;1-(3-choropropyl)-1,3-dihydro-2H-benzimidazol-2-one;1-(3-chloropropyl)-1,3-dihydro-2H-1,3-benzimidazol-2-one;1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one, AldrichCPR

Suppliers and Price of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one(~90%)
10g
$ 145.00

TRC
1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one(~90%)
100g
$ 460.00

Medical Isotopes, Inc.
1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one
200 mg
$ 290.00

Matrix Scientific
1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one 95%
1g
$ 47.00

Matrix Scientific
1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one 95%
10g
$ 143.00

Crysdot
1-(3-Chloropropyl)-1H-benzo[d]imidazol-2(3H)-one 95+%
100g
$ 557.00

Crysdot
1-(3-Chloropropyl)-1H-benzo[d]imidazol-2(3H)-one 95+%
25g
$ 396.00

Chemenu
1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one 95%
25g
$ 374.00

Chemenu
1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one 95%
100g
$ 526.00

Biosynth Carbosynth
1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one
25 g
$ 300.00

Total 96 raw suppliers

Chemical Property of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

Chemical Property:

Appearance/Colour:White to slightly beige powder
Vapor Pressure:0.017Pa at 25℃
Melting Point:115-125 °C
Refractive Index:1.57
Boiling Point:377oC
PKA:12.11±0.30(Predicted)
PSA：37.79000
Density:1.257 g/cm³
LogP:1.95850
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Water Solubility.:210 mg/L (20 ºC)
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:210.0559907
Heavy Atom Count:14
Complexity:222

Purity/Quality:

99% ^*data from raw suppliers

1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one(~90%) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn,T
Statements: 22-41-37/38-25
Safety Statements: 38-28A-45-39-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(=O)N2CCCCl
Uses 1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one is a benzimidazole derivative used in the preparation of neuroleptic and antiallergic agents.

Technology Process of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

There total 6 articles about 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 62780-84-1
1-(3-chloropropyl)-1,3-dihydro-3-(1-methylethenyl)-2H-benzimidazol-2-one

: 62780-89-6
1-(3-Chloropropyl)-1,3-dihydrobenzoimidazol-2-one

Guidance literature:: With phosphoric acid; propiononitrile; at 75 ℃; for 4h; Concentration; Temperature;

Reference yield:

: 62781-00-4
1-(3-chloropropyl)2-nitroaniline

: 62780-89-6
1-(3-Chloropropyl)-1,3-dihydrobenzoimidazol-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: xylene / 18 h / Heating

2: H₂ / 10percent Pd/C / methanol / 4 h

3: CaCl₂ / 1.5 h / 210 °C

With hydrogen; calcium chloride; palladium on activated charcoal; In methanol; xylene;
DOI:10.1007/BF00798789

Reference yield:

: 100460-82-0
(3-Chloro-propyl)-(2-nitro-phenyl)-carbamic acid ethyl ester

: 62780-89-6
1-(3-Chloropropyl)-1,3-dihydrobenzoimidazol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / methanol / 4 h

2: CaCl₂ / 1.5 h / 210 °C

With hydrogen; calcium chloride; palladium on activated charcoal; In methanol;
DOI:10.1007/BF00798789