2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate

Base Information

Chemical Name:2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate
CAS No.:359879-00-8
Molecular Formula:C₂HF₃O₂*C₃₂H₃₈N₄O₃
Molecular Weight:640.703
Hs Code.:

2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate

Synonyms:

Suppliers and Price of 2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate

There total 4 articles about 2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4 methoxyphenyl)-N-(4-methylbenzyl)-N-{1-[3(1,3dihydro-2H-benzimidazol-2-on-1-yl)propyl]piperidin-4-yl}acetamide

: 76-05-1
trifluoroacetic acid

: 359879-00-8
2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate

Guidance literature:

Reference yield:

: 104-84-7
para-methylbenzylamine

: 359879-00-8
2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium cyanoborohydride; acetic acid / methanol / 20 h / 20 °C

1.2: 1 h

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 50 h / 20 °C

3.1: hydrogenchloride / 1,4-dioxane; diethyl ether / 2 h / 20 °C

4.1: sodium carbonate; potassium iodide / acetonitrile / 20 h / 82 °C

With hydrogenchloride; sodium cyanoborohydride; sodium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; potassium iodide; In 1,4-dioxane; methanol; diethyl ether; dichloromethane; acetonitrile;

Reference yield:

: 359877-52-4
tert-butyl 4-((4-methylphenyl)methyl)aminopiperidine carboxylate

: 359879-00-8
2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-(3-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)propyl)piperidine-4-yl) acetamide trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 50 h / 20 °C

2: hydrogenchloride / 1,4-dioxane; diethyl ether / 2 h / 20 °C

3: sodium carbonate; potassium iodide / acetonitrile / 20 h / 82 °C

With hydrogenchloride; sodium carbonate; N-ethyl-N,N-diisopropylamine; potassium iodide; In 1,4-dioxane; diethyl ether; dichloromethane; acetonitrile;